-
Je něco špatně v tomto záznamu ?
New yeast-based approaches in production of palmitoleic acid
I. Kolouchová, K. Sigler, O. Schreiberová, J. Masák, T. Řezanka,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu srovnávací studie, časopisecké články, práce podpořená grantem
- MeSH
- bioreaktory mikrobiologie MeSH
- druhová specificita MeSH
- kultivační média chemie metabolismus MeSH
- kvasinky klasifikace metabolismus MeSH
- kyseliny mastné mononenasycené izolace a purifikace metabolismus MeSH
- metabolismus lipidů fyziologie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
Palmitoleic acid is found in certain dairy products and has broad applications in medicine and cosmetics. We tried to find a suitable producer of this acid among traditional biotechnological yeast species (Kluyveromyces polysporus, Torulaspora delbrueckii, Saccharomyces cerevisiae) characterized by high biomass yield and Candida krusei, Yarrowia lipolytica and Trichosporon cutaneum accumulating large amounts of lipids. The main factor affecting the content of palmitoleic acid was found to be the C/N ratio in the culture medium, with ammonium sulfate as an optimum nitrogen source leading to highest biomass yield with concomitantly increased lipid accumulation, and an increased content of ω6-linoleic acid, the precursor of prostaglandins, leukotrienes, and thromboxanes. We found that C. krusei can be conveniently used for the purpose, albeit only under certain cultivation conditions, whereas S. cerevisiae can produce high and stable amounts of palmitoleic acid in a broad range of cultivation conditions ranging from conventional to nutrient limitations.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc16020637
- 003
- CZ-PrNML
- 005
- 20160726093012.0
- 007
- ta
- 008
- 160722s2015 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.biortech.2015.06.048 $2 doi
- 024 7_
- $a 10.1016/j.biortech.2015.06.048 $2 doi
- 035 __
- $a (PubMed)26101962
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Kolouchová, Irena $u Department of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic. Electronic address: irena.kolouchova@vscht.cz.
- 245 10
- $a New yeast-based approaches in production of palmitoleic acid / $c I. Kolouchová, K. Sigler, O. Schreiberová, J. Masák, T. Řezanka,
- 520 9_
- $a Palmitoleic acid is found in certain dairy products and has broad applications in medicine and cosmetics. We tried to find a suitable producer of this acid among traditional biotechnological yeast species (Kluyveromyces polysporus, Torulaspora delbrueckii, Saccharomyces cerevisiae) characterized by high biomass yield and Candida krusei, Yarrowia lipolytica and Trichosporon cutaneum accumulating large amounts of lipids. The main factor affecting the content of palmitoleic acid was found to be the C/N ratio in the culture medium, with ammonium sulfate as an optimum nitrogen source leading to highest biomass yield with concomitantly increased lipid accumulation, and an increased content of ω6-linoleic acid, the precursor of prostaglandins, leukotrienes, and thromboxanes. We found that C. krusei can be conveniently used for the purpose, albeit only under certain cultivation conditions, whereas S. cerevisiae can produce high and stable amounts of palmitoleic acid in a broad range of cultivation conditions ranging from conventional to nutrient limitations.
- 650 _2
- $a bioreaktory $x mikrobiologie $7 D019149
- 650 _2
- $a kultivační média $x chemie $x metabolismus $7 D003470
- 650 _2
- $a kyseliny mastné mononenasycené $x izolace a purifikace $x metabolismus $7 D005229
- 650 _2
- $a metabolismus lipidů $x fyziologie $7 D050356
- 650 _2
- $a druhová specificita $7 D013045
- 650 _2
- $a kvasinky $x klasifikace $x metabolismus $7 D015003
- 655 _2
- $a srovnávací studie $7 D003160
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Sigler, Karel $u Institute of Microbiology, CAS, Vídeňská 1083, 142 20 Prague, Czech Republic.
- 700 1_
- $a Schreiberová, Olga $u Department of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.
- 700 1_
- $a Masák, Jan $u Department of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.
- 700 1_
- $a Řezanka, Tomáš $u Department of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic; Institute of Microbiology, CAS, Vídeňská 1083, 142 20 Prague, Czech Republic.
- 773 0_
- $w MED00000780 $t Bioresource technology $x 1873-2976 $g Roč. 192, č. - (2015), s. 726-34
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/26101962 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20160722 $b ABA008
- 991 __
- $a 20160726093231 $b ABA008
- 999 __
- $a ok $b bmc $g 1155307 $s 945165
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2015 $b 192 $c - $d 726-34 $e 20150616 $i 1873-2976 $m Bioresource technology $n Bioresour Technol $x MED00000780
- LZP __
- $a Pubmed-20160722
