• Je něco špatně v tomto záznamu ?

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering

AR. Perestrelo, AC. Águas, A. Rainer, G. Forte,

. 2015 ; 15 (12) : 31142-70. [pub] 20151210

Jazyk angličtina Země Švýcarsko

Typ dokumentu časopisecké články, práce podpořená grantem, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc16027820

Recent advances in biomedical technologies are mostly related to the convergence of biology with microengineering. For instance, microfluidic devices are now commonly found in most research centers, clinics and hospitals, contributing to more accurate studies and therapies as powerful tools for drug delivery, monitoring of specific analytes, and medical diagnostics. Most remarkably, integration of cellularized constructs within microengineered platforms has enabled the recapitulation of the physiological and pathological conditions of complex tissues and organs. The so-called "organ-on-a-chip" technology, which represents a new avenue in the field of advanced in vitro models, with the potential to revolutionize current approaches to drug screening and toxicology studies. This review aims to highlight recent advances of microfluidic-based devices towards a body-on-a-chip concept, exploring their technology and broad applications in the biomedical field.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc16027820
003      
CZ-PrNML
005      
20161031112517.0
007      
ta
008      
161005s2015 sz f 000 0|eng||
009      
AR
024    7_
$a 10.3390/s151229848 $2 doi
024    7_
$a 10.3390/s151229848 $2 doi
035    __
$a (PubMed)26690442
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sz
100    1_
$a Perestrelo, Ana Rubina $u International Clinical Research Center (ICRC), Integrated Center of Cellular Therapy and Regenerative Medicine (ICCT), St. Anne's University Hospital, Brno 656 91, Czech Republic. ana.rubina.perestrelo@fnusa.cz.
245    10
$a Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering / $c AR. Perestrelo, AC. Águas, A. Rainer, G. Forte,
520    9_
$a Recent advances in biomedical technologies are mostly related to the convergence of biology with microengineering. For instance, microfluidic devices are now commonly found in most research centers, clinics and hospitals, contributing to more accurate studies and therapies as powerful tools for drug delivery, monitoring of specific analytes, and medical diagnostics. Most remarkably, integration of cellularized constructs within microengineered platforms has enabled the recapitulation of the physiological and pathological conditions of complex tissues and organs. The so-called "organ-on-a-chip" technology, which represents a new avenue in the field of advanced in vitro models, with the potential to revolutionize current approaches to drug screening and toxicology studies. This review aims to highlight recent advances of microfluidic-based devices towards a body-on-a-chip concept, exploring their technology and broad applications in the biomedical field.
650    _2
$a zvířata $7 D000818
650    _2
$a biomedicínský výzkum $7 D035843
650    _2
$a lidé $7 D006801
650    _2
$a myši $7 D051379
650    _2
$a mikroelektromechanické systémy $7 D055617
650    12
$a mikrofluidní analytické techniky $7 D046210
650    12
$a biologické modely $7 D008954
650    12
$a čipová analýza tkání $7 D046888
650    12
$a tkáňové inženýrství $7 D023822
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
655    _2
$a přehledy $7 D016454
700    1_
$a Águas, Ana C P $u Center for Biomedical Research, University of Algarve, Faro 8005-139, Portugal. acaguas@ualg.pt.
700    1_
$a Rainer, Alberto $u Tissue Engineering Unit, Università Campus Bio-Medico di Roma, Rome 00128, Italy. a.rainer@unicampus.it.
700    1_
$a Forte, Giancarlo $u International Clinical Research Center (ICRC), Integrated Center of Cellular Therapy and Regenerative Medicine (ICCT), St. Anne's University Hospital, Brno 656 91, Czech Republic. giancarlo.forte@fnusa.cz. Department of Biomaterials Science, University of Turku, Turku 20014, Finland. giancarlo.forte@fnusa.cz.
773    0_
$w MED00008309 $t Sensors (Basel, Switzerland) $x 1424-8220 $g Roč. 15, č. 12 (2015), s. 31142-70
856    41
$u https://pubmed.ncbi.nlm.nih.gov/26690442 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20161005 $b ABA008
991    __
$a 20161031112441 $b ABA008
999    __
$a ok $b bmc $g 1166134 $s 952450
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2015 $b 15 $c 12 $d 31142-70 $e 20151210 $i 1424-8220 $m Sensors $n Sensors Basel $x MED00008309
LZP    __
$a Pubmed-20161005

Najít záznam

Citační ukazatele

    Možnosti archivace