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Recent developments and applications of capillary and microchip electrophoresis in proteomic and peptidomic analyses

S. Štěpánová, V. Kašička,

. 2016 ; 39 (1) : 198-211. [pub] 20151119

Jazyk angličtina Země Německo

Typ dokumentu časopisecké články, práce podpořená grantem, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc17000930

This review presents recent developments and applications of capillary and microchip electromigration methods in proteomics and peptidomics. Sample preparation methods as well as instrumental innovations in the coupling of these advanced electromigration methods with mass spectrometry detection employed in proteomic and peptidomic analyses are presented. Interesting applications of various capillary electromigration methods in bottom-up as well as top-down proteomics, including investigation of post-translational modifications of proteins are described. In addition, several examples of the use of capillary electromigration methods combined with mass spectrometry detection in clinical proteomics and peptidomics are demonstrated.

Citace poskytuje Crossref.org

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