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Superparamagnetic iron oxide-enhanced magnetic resonance for imaging cardiac inflammation. A minireview
H. Podrouzkova, V. Feitova, R. Panovsky, J. Meluzin, M. Orban
Jazyk angličtina Země Česko
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
NLK
Directory of Open Access Journals
od 2001
Free Medical Journals
od 1998
Medline Complete (EBSCOhost)
od 2007-06-01
ROAD: Directory of Open Access Scholarly Resources
od 2001
- MeSH
- dextrany farmakokinetika MeSH
- kontrastní látky farmakokinetika MeSH
- lidé MeSH
- magnetická rezonanční tomografie metody MeSH
- magnetické nanočástice MeSH
- myokard patologie MeSH
- rejekce štěpu diagnostické zobrazování metabolismus MeSH
- transplantace srdce * MeSH
- velikost částic MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
BACKGROUND: Advances in nanotechnology have lead to the development of a novel contrast media for Magnetic Resonance Imaging (MRI) - the superparamagnetic iron oxide nanoparticle (SPIO). SPIO nanoparticles are used to image inflammation on the cellular level in various settings. This review covers the physicochemical characteristics of SPIO particles as well as relevant animal and clinical studies and discusses the potential of SPIO particles to image cardiac inflammation including cardiac graft rejection. METHODS: We searched the scientific biomedical databases Medline/PubMed, BioMedCentral, Google Scholar, Ovid and, ProQuest from to 2000 to 2013 for publications relevant to the topic. CONCLUSIONS: SPIO nanoparticles due to their unique properties could become a useful tool in imaging cardiac inflammation. However, the task is to find a suitable particle size and coating with corresponding pharmacokinetics, establish the right dose and MRI scan timing for individual applications.
Citace poskytuje Crossref.org
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