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Musculoskeletal pain and vitamin D feficiency in children: a pilot follow-up study of vitamin D therapy in musculoskeletal/orthopedic conditions [Muskuloskeletální bolest a deficit vitaminu D u dětí: pilotní studie sledování terapie vitaminem D u muskuloskeletálních ortopedických onemocnění]
Z. Blagojevic, V. Nikolic, D. Kisic-Tepavcevic, Z. Terzic Supic, R. Kovacevic, Z. Zivkovic, D. Stevanovic
Jazyk angličtina Země Česko
Typ dokumentu časopisecké články
PubMed
26936061
DOI
10.55095/achot2016/003
Knihovny.cz E-zdroje
- MeSH
- dítě MeSH
- lidé MeSH
- měření bolesti účinky léků MeSH
- mladiství MeSH
- muskuloskeletální bolest krev diagnóza farmakoterapie MeSH
- muskuloskeletální nemoci diagnóza farmakoterapie MeSH
- následné studie MeSH
- nedostatek vitaminu D krev diagnóza farmakoterapie MeSH
- pilotní projekty MeSH
- prevalence MeSH
- únava farmakoterapie MeSH
- vitamin D analogy a deriváty krev terapeutické užití MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
PURPOSE OF THE STUDY: The prevalence of vitamin D deficiency in pediatric populations is high. In the present study we analyzed associations between vitamin D therapy and pain, mobility, fatigue, and daily functioning in children with musculoskeletal/orthopedic conditions suffering from chronic and recurrent pain, but also diagnosed with vitamin D deficiency. MATERIAL AND METHODS: Children with different musculoskeletal/orthopedic conditions and vitamin D deficiency were prescribed to receive vitamin D over 6 months. Thirty-five children (18 males; age 10.48 ± 3.87 years) completed a 6-month follow-up. Self- and parent/proxy rating scales were used to evaluate pain, movement, fatigue, and daily functioning. RESULTS: At a six-month follow-up assessment involving child- and parent-reported scores, worst pain intensity significantly decreased (p ≤ 0.03) after vitamin D therapy, as well as functioning problems related to pain (p ≤ 0.01). The children reported better movement and balance with less fatigue. The parents reported better functioning in everyday activities of their children. CONCLUSION: This pilot study showed that vitamin D therapy possibly reduces pain intensity and improves mobility and daily functioning in children with musculoskeletal/orthopedic disorders, chronic recurrent pain, and vitamin D deficiency. Further follow-up and randomized studies are required in order to assess the validity of clinical recommendations.
Clinic for Neurology and Psychiatry for Children and Youth Belgrade Serbia
Institute for Orthopedic Surgery Banjica Belgrade Serbia
Institute of Epidemiology Belgrade University School of Medicine Belgrade Serbia
Institute of Social Medicine Belgrade University School of Medicine Belgrade Serbia
Muskuloskeletální bolest a deficit vitaminu D u dětí: pilotní studie sledování terapie vitaminem D u muskuloskeletálních ortopedických onemocnění
Citace poskytuje Crossref.org
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