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Clostridium difficile PCR ribotypes 001 and 176 - the common denominator of C. difficile infection epidemiology in the Czech Republic, 2014
M. Krutova, J. Matejkova, EJ. Kuijper, P. Drevinek, O. Nyc, . ,
Jazyk angličtina Země Švédsko
Typ dokumentu časopisecké články
Grantová podpora
NT14209
MZ0
CEP - Centrální evidence projektů
Digitální knihovna NLK
Plný text - Článek
Zdroj
NLK
Directory of Open Access Journals
od 1996
Free Medical Journals
od 1995
Freely Accessible Science Journals
od 1995-09-01
PubMed Central
od 2016
Europe PubMed Central
od 2016
Open Access Digital Library
od 1996-01-01
Open Access Digital Library
od 2016-01-01
Medline Complete (EBSCOhost)
od 2010-07-01
ROAD: Directory of Open Access Scholarly Resources
od 1995
- MeSH
- Clostridioides difficile klasifikace genetika izolace a purifikace MeSH
- elektroforéza kapilární MeSH
- feces mikrobiologie MeSH
- incidence MeSH
- klostridiové infekce diagnóza epidemiologie MeSH
- lidé MeSH
- minisatelitní repetice MeSH
- nemocnice statistika a číselné údaje MeSH
- oznamovací povinnost MeSH
- polymerázová řetězová reakce MeSH
- průjem epidemiologie mikrobiologie MeSH
- ribotypizace metody MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika epidemiologie MeSH
In 2014, 18 hospitals in the Czech Republic participated in a survey of the incidence of Clostridium difficile infections (CDI) in the country. The mean CDI incidence was 6.1 (standard deviation (SD):7.2) cases per 10,000 patient bed-days and 37.8 cases (SD: 41.4) per 10,000 admissions. The mean CDI testing frequency was 39.5 tests (SD: 25.4) per 10,000 patient bed-days and 255.8 tests (SD: 164.0) per 10,000 admissions. A total of 774 C. difficile isolates were investigated, of which 225 (29%) belonged to PCR ribotype 176, and 184 isolates (24%) belonged to PCR ribotype 001. Multilocus variable-number tandem repeat analysis (MLVA) revealed 27 clonal complexes formed by 84% (190/225) of PCR ribotype 176 isolates, and 14 clonal complexes formed by 77% (141/184) of PCR ribotype 001 isolates. Clonal clusters of PCR ribotypes 176 and 001 were observed in 11 and 7 hospitals, respectively. Our data demonstrate the spread of two C. difficile PCR ribotypes within 18 hospitals in the Czech Republic, stressing the importance of standardising CDI testing protocols and implementing mandatory CDI surveillance in the country.
Citace poskytuje Crossref.org
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