-
Something wrong with this record ?
High-molecular-weight HPMA-based polymer drug carriers for delivery to tumor
L. Kostka, T. Etrych
Language English Country Czech Republic
Document type Journal Article, Review
NLK
Directory of Open Access Journals
from 1991
Free Medical Journals
from 1998
ProQuest Central
from 2005-01-01
Medline Complete (EBSCOhost)
from 2006-01-01
Nursing & Allied Health Database (ProQuest)
from 2005-01-01
Health & Medicine (ProQuest)
from 2005-01-01
ROAD: Directory of Open Access Scholarly Resources
from 1998
- MeSH
- Methacrylates * MeSH
- Micelles MeSH
- Nanoparticles MeSH
- Drug Carriers * MeSH
- Polymers * MeSH
- Prodrugs MeSH
- Antineoplastic Agents * MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
In this work, design and synthesis of high-molecular-weight N-(2-hydroxypropyl)methacrylamide-based polymer drug delivery systems tailored for cancer therapy is summarized. Moreover, the influence of their architecture on tumor accumulation and in vivo anti-cancer efficacy is discussed. Mainly, the high-molecular-weight delivery systems, such as branched, grafted, multi-block, star-like or micellar systems, with molecular weights greater than the renal threshold are discussed and reviewed in detail.
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc17021002
- 003
- CZ-PrNML
- 005
- 20190814101004.0
- 007
- ta
- 008
- 170623s2016 xr d f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.33549/physiolres.933420 $2 doi
- 035 __
- $a (PubMed)27762584
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xr
- 100 1_
- $a Kostka, Libor $u Department of Biomedicinal Polymers, Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic $7 xx0232772
- 245 10
- $a High-molecular-weight HPMA-based polymer drug carriers for delivery to tumor / $c L. Kostka, T. Etrych
- 520 9_
- $a In this work, design and synthesis of high-molecular-weight N-(2-hydroxypropyl)methacrylamide-based polymer drug delivery systems tailored for cancer therapy is summarized. Moreover, the influence of their architecture on tumor accumulation and in vivo anti-cancer efficacy is discussed. Mainly, the high-molecular-weight delivery systems, such as branched, grafted, multi-block, star-like or micellar systems, with molecular weights greater than the renal threshold are discussed and reviewed in detail.
- 650 12
- $a protinádorové látky $7 D000970
- 650 12
- $a nosiče léků $7 D004337
- 650 12
- $a methakryláty $7 D008689
- 650 _2
- $a micely $7 D008823
- 650 _2
- $a nanočástice $7 D053758
- 650 12
- $a polymery $7 D011108
- 650 _2
- $a prekurzory léčiv $7 D011355
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a přehledy $7 D016454
- 700 1_
- $a Etrych, Tomáš $7 xx0068504 $u Department of Biomedicinal Polymers, Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic
- 773 0_
- $w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 65, Suppl. 2 (2016), s. S179-S190
- 773 0_
- $t Recent achievements from Otto Wichterle Innovation Centre of Polymeric Materials and Biocev Research Projects $x 1802-9973 $g Roč. 65, Suppl. 2 (2016), s. S179-S190 $w MED00196542
- 856 41
- $u http://www.biomed.cas.cz/physiolres/ $y domovská stránka časopisu
- 910 __
- $a ABA008 $b A 4120 $c 266 $y 4 $z 0
- 990 __
- $a 20170623 $b ABA008
- 991 __
- $a 20190814101230 $b ABA008
- 999 __
- $a ok $b bmc $g 1236298 $s 981875
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2016 $b 65 $c Suppl. 2 $d S179-S190 $i 1802-9973 $m Physiological research $n Physiol. Res. (Print) $x MED00003824
- BMC __
- $a 2016 $b 65 $c Suppl. 2 $d S179-S190 $i 1802-9973 $m Recent achievements from Otto Wichterle Innovation Centre of Polymeric Materials and Biocev Research Projects $x MED00196542
- LZP __
- $b NLK118 $a Pubmed-20170623
