Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Stem Cells and Labeling for Spinal Cord Injury

M. Gazdic, V. Volarevic, A. Arsenijevic, S. Erceg, V. Moreno-Manzano, N. Arsenijevic, M. Stojkovic,

. 2016 ; 18 (1) : . [pub] 20161226

Jazyk angličtina Země Švýcarsko

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc17023395

Spinal cord injury (SCI) is a devastating condition that usually results in sudden and long-lasting locomotor and sensory neuron degeneration below the lesion site. During the last two decades, the search for new therapies has been revolutionized with the improved knowledge of stem cell (SC) biology. SCs therapy offers several attractive strategies for spinal cord repair. The transplantation of SCs promotes remyelination, neurite outgrowth and axonal elongation, and activates resident or transplanted progenitor cells across the lesion cavity. However, optimized growth and differentiation protocols along with reliable safety assays should be established prior to the clinical application of SCs. Additionally, the ideal method of SCs labeling for efficient cell tracking after SCI remains a challenging issue that requires further investigation. This review summarizes the current findings on the SCs-based therapeutic strategies, and compares different SCs labeling approaches for SCI.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc17023395
003      
CZ-PrNML
005      
20170720124151.0
007      
ta
008      
170720s2016 sz f 000 0|eng||
009      
AR
024    7_
$a 10.3390/ijms18010006 $2 doi
035    __
$a (PubMed)28035961
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sz
100    1_
$a Gazdic, Marina $u Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. marinagazdic87@gmail.com.
245    10
$a Stem Cells and Labeling for Spinal Cord Injury / $c M. Gazdic, V. Volarevic, A. Arsenijevic, S. Erceg, V. Moreno-Manzano, N. Arsenijevic, M. Stojkovic,
520    9_
$a Spinal cord injury (SCI) is a devastating condition that usually results in sudden and long-lasting locomotor and sensory neuron degeneration below the lesion site. During the last two decades, the search for new therapies has been revolutionized with the improved knowledge of stem cell (SC) biology. SCs therapy offers several attractive strategies for spinal cord repair. The transplantation of SCs promotes remyelination, neurite outgrowth and axonal elongation, and activates resident or transplanted progenitor cells across the lesion cavity. However, optimized growth and differentiation protocols along with reliable safety assays should be established prior to the clinical application of SCs. Additionally, the ideal method of SCs labeling for efficient cell tracking after SCI remains a challenging issue that requires further investigation. This review summarizes the current findings on the SCs-based therapeutic strategies, and compares different SCs labeling approaches for SCI.
650    _2
$a zvířata $7 D000818
650    _2
$a buněčný tracking $x metody $7 D058948
650    _2
$a lidé $7 D006801
650    _2
$a regenerace nervu $7 D009416
650    _2
$a nervové kmenové buňky $x cytologie $x transplantace $7 D058953
650    _2
$a neurogeneze $7 D055495
650    _2
$a poranění míchy $x diagnostické zobrazování $x patologie $x terapie $7 D013119
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Volarevic, Vladislav $u Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. drvolarevic@yahoo.com.
700    1_
$a Arsenijevic, Aleksandar $u Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. aleksandar@medf.kg.ac.rs. $7 gn_A_00008939
700    1_
$a Erceg, Slaven $u Stem Cell Therapies in Neurodegenerative Diseases Laboratory, Centro de Investigación Príncipe Felipe, E-46012 Valencia, Spain. serceg@cipf.es. National Stem Cell Bank-Valencia Node, Biomolecular and Bioinformatics Resources Platform PRB2, ISCIII, Research Center "Principe Felipe", c/Eduardo Primo Yúfera 3, 46012 Valencia, Spain. serceg@cipf.es. Institute of Experimental Medicine, Department of Neuroscience, Academy of Science of the Czech Republic, Videnská 1083, 142 20 Prague 4, Czech Republic. serceg@cipf.es.
700    1_
$a Moreno-Manzano, Victoria $u Neuronal and Tissue Regeneration Laboratory, Centro de Investigación Príncipe Felipe, E-46012 Valencia, Spain. vmorenom@cipf.es.
700    1_
$a Arsenijevic, Nebojsa $u Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. arne@medf.kg.ac.rs. $7 gn_A_00008940
700    1_
$a Stojkovic, Miodrag $u Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia. mstojkovic@spebo.co.rs. Spebo Medical, 16000 Leskovac, Serbia. mstojkovic@spebo.co.rs.
773    0_
$w MED00176142 $t International journal of molecular sciences $x 1422-0067 $g Roč. 18, č. 1 (2016)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/28035961 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20170720 $b ABA008
991    __
$a 20170720124644 $b ABA008
999    __
$a ok $b bmc $g 1239076 $s 984308
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2016 $b 18 $c 1 $e 20161226 $i 1422-0067 $m International journal of molecular sciences $n Int J Mol Sci $x MED00176142
LZP    __
$a Pubmed-20170720

Najít záznam

Citační ukazatele

Možnosti archivace