-
Something wrong with this record ?
Single-Phase Versus Multiphase CT Angiography in Middle Cerebral Artery Clot Detection-Benefits for Less Experienced Radiologists and Neurologists
O. Volny, P. Cimflova, P. Kadlecova, P. Vanek, J. Vanicek, BK. Menon, R. Mikulik,
Language English Country United States
Document type Journal Article
- MeSH
- Middle Cerebral Artery diagnostic imaging MeSH
- Time Factors MeSH
- Stroke complications MeSH
- Computed Tomography Angiography methods MeSH
- Intracranial Thrombosis diagnostic imaging etiology MeSH
- Cohort Studies MeSH
- Humans MeSH
- Neurologists psychology MeSH
- Radiologists psychology MeSH
- Sensitivity and Specificity MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
OBJECTIVES: CT angiography (CTA) is recommended as a standard of stroke imaging. We investigated accuracy and precision of standard or single-phase CTA as compared with novel technique or multiphase CTA in clot detection in the middle cerebral artery. METHODS: Twenty single-phase CTA and twenty multiphase CTA with prevailing M2 occlusion were assessed by 10 radiologists and 10 neurologists blinded to clinical information (7 less experienced and 3 experienced). Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated as compared with reading by two seniors. Reliability was calculated using Krippendorff's alpha (K-alpha). RESULTS: Sensitivity, specificity, PPV, and NPV of single-phase CTA compared with multiphase CTA for M2 clot presence were, respectively, .86, .75, .90, and .67 versus .88, .82, .92, and .72. For secondary or distal clots, sensitivity, specificity, PPV, and NPV of single-phase CTA compared with multiphase CTA were .41, .83, .50, and .78 versus .65, .77, .71, and .67. Agreement increased significantly in favor of multiphase CTA for detection of primary clots from moderate (.43) to substantial (.65) in less experienced radiologists and from slight (.10) to moderate (.30) in less experienced neurologists. Agreement significantly increased for distal or secondary clot detection in favor of multiphase CTA from fair (.24) to moderate (.49) in experienced radiologists and from slight (.12) to moderate (.46) in experienced neurologists. CONCLUSIONS: Multiphase CTA is a reliable imaging tool in M2 clot detection and might represent a beneficial imaging tool in clot detection for less experienced physicians.
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc17023716
- 003
- CZ-PrNML
- 005
- 20170720122324.0
- 007
- ta
- 008
- 170720s2017 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.jstrokecerebrovasdis.2016.08.023 $2 doi
- 035 __
- $a (PubMed)27612627
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Volny, Ondrej $u Stroke Research Program, International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic; Department of Neurology, Faculty of Medicine, St. Anne's University Hospital, Masaryk University, Brno, Czech Republic. Electronic address: 214565@mail.muni.cz.
- 245 10
- $a Single-Phase Versus Multiphase CT Angiography in Middle Cerebral Artery Clot Detection-Benefits for Less Experienced Radiologists and Neurologists / $c O. Volny, P. Cimflova, P. Kadlecova, P. Vanek, J. Vanicek, BK. Menon, R. Mikulik,
- 520 9_
- $a OBJECTIVES: CT angiography (CTA) is recommended as a standard of stroke imaging. We investigated accuracy and precision of standard or single-phase CTA as compared with novel technique or multiphase CTA in clot detection in the middle cerebral artery. METHODS: Twenty single-phase CTA and twenty multiphase CTA with prevailing M2 occlusion were assessed by 10 radiologists and 10 neurologists blinded to clinical information (7 less experienced and 3 experienced). Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated as compared with reading by two seniors. Reliability was calculated using Krippendorff's alpha (K-alpha). RESULTS: Sensitivity, specificity, PPV, and NPV of single-phase CTA compared with multiphase CTA for M2 clot presence were, respectively, .86, .75, .90, and .67 versus .88, .82, .92, and .72. For secondary or distal clots, sensitivity, specificity, PPV, and NPV of single-phase CTA compared with multiphase CTA were .41, .83, .50, and .78 versus .65, .77, .71, and .67. Agreement increased significantly in favor of multiphase CTA for detection of primary clots from moderate (.43) to substantial (.65) in less experienced radiologists and from slight (.10) to moderate (.30) in less experienced neurologists. Agreement significantly increased for distal or secondary clot detection in favor of multiphase CTA from fair (.24) to moderate (.49) in experienced radiologists and from slight (.12) to moderate (.46) in experienced neurologists. CONCLUSIONS: Multiphase CTA is a reliable imaging tool in M2 clot detection and might represent a beneficial imaging tool in clot detection for less experienced physicians.
- 650 _2
- $a kohortové studie $7 D015331
- 650 _2
- $a CT angiografie $x metody $7 D000072226
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a intrakraniální trombóza $x diagnostické zobrazování $x etiologie $7 D020767
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a arteria cerebri media $x diagnostické zobrazování $7 D020768
- 650 _2
- $a neurologové $x psychologie $7 D000072141
- 650 _2
- $a radiologové $x psychologie $7 D000072177
- 650 _2
- $a senzitivita a specificita $7 D012680
- 650 _2
- $a cévní mozková příhoda $x komplikace $7 D020521
- 650 _2
- $a časové faktory $7 D013997
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Cimflova, Petra $u Stroke Research Program, International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic; Department of Medical Imaging, Faculty of Medicine, St. Anne's University Hospital, Masaryk University, Brno, Czech Republic.
- 700 1_
- $a Kadlecova, Pavla $u Stroke Research Program, International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.
- 700 1_
- $a Vanek, Petr $u Faculty of Medicine, Masaryk University, Brno, Czech Republic.
- 700 1_
- $a Vanicek, Jiri $u Department of Medical Imaging, Faculty of Medicine, St. Anne's University Hospital, Masaryk University, Brno, Czech Republic.
- 700 1_
- $a Menon, Bijoy K $u Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
- 700 1_
- $a Mikulik, Robert $u Stroke Research Program, International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic; Department of Neurology, Faculty of Medicine, St. Anne's University Hospital, Masaryk University, Brno, Czech Republic.
- 773 0_
- $w MED00167194 $t Journal of stroke and cerebrovascular diseases the official journal of National Stroke Association $x 1532-8511 $g Roč. 26, č. 1 (2017), s. 19-24
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/27612627 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20170720 $b ABA008
- 991 __
- $a 20170720122817 $b ABA008
- 999 __
- $a ok $b bmc $g 1239397 $s 984629
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2017 $b 26 $c 1 $d 19-24 $e 20160906 $i 1532-8511 $m Journal of stroke and cerebrovascular diseases $n J Stroke Cerebrovasc Dis $x MED00167194
- LZP __
- $a Pubmed-20170720
