• Je něco špatně v tomto záznamu ?

In vitro degradation of ZM21 magnesium alloy in simulated body fluids

A. Witecka, A. Bogucka, A. Yamamoto, K. Máthis, T. Krajňák, J. Jaroszewicz, W. Święszkowski,

. 2016 ; 65 (-) : 59-69. [pub] 20160408

Jazyk angličtina Země Nizozemsko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc17024001

In vitro degradation behavior of squeeze cast (CAST) and equal channel angular pressed (ECAP) ZM21 magnesium alloy (2.0wt% Zn-0.98wt% Mn) was studied using immersion tests up to 4w in three different biological environments. Hanks' Balanced Salt Solution (Hanks), Earle's Balanced Salt Solution (Earle) and Eagle minimum essential medium supplemented with 10% (v/v) fetal bovine serum (E-MEM+10% FBS) were used to investigate the effect of carbonate buffer system, organic compounds and material processing on the degradation behavior of the ZM21 alloy samples. Corrosion rate of the samples was evaluated by their Mg(2+) ion release, weight loss and volume loss. In the first 24h, the corrosion rate sequence of the CAST samples was as following: Hanks>E-MEM+10% FBS>Earle. However, in longer immersion periods, the corrosion rate sequence was Earle>E-MEM+10% FBS≥Hanks. Strong buffering effect provided by carbonate buffer system helped to maintain the pH avoiding drastic increase of the corrosion rate of ZM21 in the initial stage of immersion. Organic compounds also contributed to maintain the pH of the fluid. Moreover, they adsorbed on the sample surface and formed an additional barrier on the insoluble salt layer, which was effective to retard the corrosion of CAST samples. In case of ECAP, however, this effect was overcome by the occurrence of strong localized corrosion due to the lower pH of the medium. Corrosion of ECAP samples was much greater than that of CAST, especially in Hanks, due to higher sensitivity of ECAP to localized corrosion and the presence of Cl(-). The present work demonstrates the importance of using an appropriate solution for a reliable estimation of the degradation rate of Mg-base degradable implants in biological environments, and concludes that the most appropriate solution for this purpose is E-MEM+10% FBS, which has the closest chemical composition to human blood plasma.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc17024001
003      
CZ-PrNML
005      
20170720123156.0
007      
ta
008      
170720s2016 ne f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.msec.2016.04.019 $2 doi
035    __
$a (PubMed)27157728
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a ne
100    1_
$a Witecka, Agnieszka $u National Institute for Materials Science, Biomaterials Unit, Biometal Group, Tsukuba, Ibaraki 305-0044, Japan; Warsaw University of Technology, Faculty of Materials Science and Engineering, 141 Woloska Street, Warsaw 02-507, Poland.
245    10
$a In vitro degradation of ZM21 magnesium alloy in simulated body fluids / $c A. Witecka, A. Bogucka, A. Yamamoto, K. Máthis, T. Krajňák, J. Jaroszewicz, W. Święszkowski,
520    9_
$a In vitro degradation behavior of squeeze cast (CAST) and equal channel angular pressed (ECAP) ZM21 magnesium alloy (2.0wt% Zn-0.98wt% Mn) was studied using immersion tests up to 4w in three different biological environments. Hanks' Balanced Salt Solution (Hanks), Earle's Balanced Salt Solution (Earle) and Eagle minimum essential medium supplemented with 10% (v/v) fetal bovine serum (E-MEM+10% FBS) were used to investigate the effect of carbonate buffer system, organic compounds and material processing on the degradation behavior of the ZM21 alloy samples. Corrosion rate of the samples was evaluated by their Mg(2+) ion release, weight loss and volume loss. In the first 24h, the corrosion rate sequence of the CAST samples was as following: Hanks>E-MEM+10% FBS>Earle. However, in longer immersion periods, the corrosion rate sequence was Earle>E-MEM+10% FBS≥Hanks. Strong buffering effect provided by carbonate buffer system helped to maintain the pH avoiding drastic increase of the corrosion rate of ZM21 in the initial stage of immersion. Organic compounds also contributed to maintain the pH of the fluid. Moreover, they adsorbed on the sample surface and formed an additional barrier on the insoluble salt layer, which was effective to retard the corrosion of CAST samples. In case of ECAP, however, this effect was overcome by the occurrence of strong localized corrosion due to the lower pH of the medium. Corrosion of ECAP samples was much greater than that of CAST, especially in Hanks, due to higher sensitivity of ECAP to localized corrosion and the presence of Cl(-). The present work demonstrates the importance of using an appropriate solution for a reliable estimation of the degradation rate of Mg-base degradable implants in biological environments, and concludes that the most appropriate solution for this purpose is E-MEM+10% FBS, which has the closest chemical composition to human blood plasma.
650    _2
$a slitiny $x chemie $7 D000497
650    _2
$a zvířata $7 D000818
650    _2
$a tělesné tekutiny $x chemie $7 D001826
650    _2
$a skot $7 D002417
650    _2
$a koroze $7 D003343
650    _2
$a kultivační média $x chemie $7 D003470
650    _2
$a lidé $7 D006801
650    _2
$a koncentrace vodíkových iontů $7 D006863
650    _2
$a isotonické roztoky $x chemie $7 D007552
650    _2
$a hořčík $x chemie $7 D008274
650    _2
$a mikroskopie elektronová rastrovací $7 D008855
650    _2
$a spektrometrie rentgenová emisní $7 D013052
650    _2
$a povrchové vlastnosti $7 D013499
655    _2
$a časopisecké články $7 D016428
700    1_
$a Bogucka, Aleksandra $u Warsaw University of Technology, Faculty of Materials Science and Engineering, 141 Woloska Street, Warsaw 02-507, Poland.
700    1_
$a Yamamoto, Akiko $u National Institute for Materials Science, Biomaterials Unit, Biometal Group, Tsukuba, Ibaraki 305-0044, Japan. Electronic address: yamamoto.akiko@nims.go.jp.
700    1_
$a Máthis, Kristián $u Charles University, Faculty of Mathematics and Physics, Department of Physics of Materials, Ke Karlovu 5,121 16 Praha 2, Czech Republic.
700    1_
$a Krajňák, Tomáš $u Charles University, Faculty of Mathematics and Physics, Department of Physics of Materials, Ke Karlovu 5,121 16 Praha 2, Czech Republic.
700    1_
$a Jaroszewicz, Jakub $u Warsaw University of Technology, Faculty of Materials Science and Engineering, 141 Woloska Street, Warsaw 02-507, Poland.
700    1_
$a Święszkowski, Wojciech $u Warsaw University of Technology, Faculty of Materials Science and Engineering, 141 Woloska Street, Warsaw 02-507, Poland.
773    0_
$w MED00184559 $t Materials science & engineering. C, Materials for biological applications $x 1873-0191 $g Roč. 65, č. - (2016), s. 59-69
856    41
$u https://pubmed.ncbi.nlm.nih.gov/27157728 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20170720 $b ABA008
991    __
$a 20170720123649 $b ABA008
999    __
$a ok $b bmc $g 1239682 $s 984914
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2016 $b 65 $c - $d 59-69 $e 20160408 $i 1873-0191 $m Materials science & engineering. C, Materials for biological applications $n Mater Sci Eng C Mater Biol Appl $x MED00184559
LZP    __
$a Pubmed-20170720

Najít záznam

Citační ukazatele

Možnosti archivace