Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Formulation, Characterization and Properties of Hemp Seed Oil and Its Emulsions

V. Mikulcová, V. Kašpárková, P. Humpolíček, L. Buňková,

. 2017 ; 22 (5) : . [pub] 20170427

Language English Country Switzerland

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc17030855

The formulation, characterization, and anticipated antibacterial properties of hemp seed oil and its emulsions were investigated. The oil obtained from the seeds of Cannabis sativa L. in refined and unrefined form was characterized using iodine, saponification, acid values, and gas chromatography, and was employed for the preparation of stable oil-in-water emulsions. The emulsions were prepared using pairs of non-ionic surfactants (Tween, Span). The effects of the emulsification method (spontaneous emulsification vs. high-intensity stirring), hydrophilic lipophilic balance (HLB), type and concentration of surfactant, and oil type on the size and distribution of the emulsion particles were investigated. It was found that the ability to form stable emulsions with small, initial particle sizes is primarily dependent on the given method of preparation and the HLB value. The most efficient method of emulsification that afforded the best emulsions with the smallest particles (151 ± 1 nm) comprised the high-energy method, and emulsions stable over the long-term were observed at HBL 9 with 10 wt % concentration of surfactants. Under high-intensity emulsification, refined and unrefined oils performed similarly. The oils as well as their emulsions were tested against the growth of selected bacteria using the disk diffusion and broth microdilution methods. The antibacterial effect of hemp seed oil was documented against Micrococcus luteus and Staphylococcus aureus subsp. aureus. The formulated emulsions did not exhibit the antibacterial activity that had been anticipated.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc17030855
003      
CZ-PrNML
005      
20171030134151.0
007      
ta
008      
171025s2017 sz f 000 0|eng||
009      
AR
024    7_
$a 10.3390/molecules22050700 $2 doi
035    __
$a (PubMed)28448475
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sz
100    1_
$a Mikulcová, Veronika $u Department of Fat, Surfactant and Cosmetics Technology, Faculty of Technology, Tomas Bata University in Zlin, nam. T. G. Masaryka 5555, 760 01 Zlin, Czech Republic. mikulcova@ft.utb.cz.
245    10
$a Formulation, Characterization and Properties of Hemp Seed Oil and Its Emulsions / $c V. Mikulcová, V. Kašpárková, P. Humpolíček, L. Buňková,
520    9_
$a The formulation, characterization, and anticipated antibacterial properties of hemp seed oil and its emulsions were investigated. The oil obtained from the seeds of Cannabis sativa L. in refined and unrefined form was characterized using iodine, saponification, acid values, and gas chromatography, and was employed for the preparation of stable oil-in-water emulsions. The emulsions were prepared using pairs of non-ionic surfactants (Tween, Span). The effects of the emulsification method (spontaneous emulsification vs. high-intensity stirring), hydrophilic lipophilic balance (HLB), type and concentration of surfactant, and oil type on the size and distribution of the emulsion particles were investigated. It was found that the ability to form stable emulsions with small, initial particle sizes is primarily dependent on the given method of preparation and the HLB value. The most efficient method of emulsification that afforded the best emulsions with the smallest particles (151 ± 1 nm) comprised the high-energy method, and emulsions stable over the long-term were observed at HBL 9 with 10 wt % concentration of surfactants. Under high-intensity emulsification, refined and unrefined oils performed similarly. The oils as well as their emulsions were tested against the growth of selected bacteria using the disk diffusion and broth microdilution methods. The antibacterial effect of hemp seed oil was documented against Micrococcus luteus and Staphylococcus aureus subsp. aureus. The formulated emulsions did not exhibit the antibacterial activity that had been anticipated.
650    _2
$a antibakteriální látky $x chemie $x izolace a purifikace $x farmakologie $7 D000900
650    _2
$a Cannabis $x chemie $7 D002188
650    _2
$a emulze $7 D004655
650    _2
$a hydrofobní a hydrofilní interakce $7 D057927
650    _2
$a mikrobiální testy citlivosti $7 D008826
650    _2
$a Micrococcus luteus $x účinky léků $7 D016982
650    _2
$a velikost částic $7 D010316
650    _2
$a rostlinné extrakty $x chemie $x izolace a purifikace $x farmakologie $7 D010936
650    _2
$a oleje rostlin $x chemie $x izolace a purifikace $x farmakologie $7 D010938
650    _2
$a semena rostlinná $x chemie $7 D012639
650    _2
$a Staphylococcus aureus $x účinky léků $7 D013211
655    _2
$a časopisecké články $7 D016428
700    1_
$a Kašpárková, Věra $u Department of Fat, Surfactant and Cosmetics Technology, Faculty of Technology, Tomas Bata University in Zlin, nam. T. G. Masaryka 5555, 760 01 Zlin, Czech Republic. vkasparkova@ft.utb.cz. Centre of Polymer Systems, Tomas Bata University in Zlin, nam. T. G. Masaryka 5555, 760 01 Zlin, Czech Republic. vkasparkova@ft.utb.cz.
700    1_
$a Humpolíček, Petr $u Centre of Polymer Systems, Tomas Bata University in Zlin, nam. T. G. Masaryka 5555, 760 01 Zlin, Czech Republic. humpolicek@ft.utb.cz. Polymer Centre, Faculty of Technology, Tomas Bata University in Zlin, 760 01 Zlin, Czech Republic. humpolicek@ft.utb.cz.
700    1_
$a Buňková, Leona $u Department of Environmental Protection and Engineering, Faculty of Technology, Tomas Bata University in Zlin, nam. T. G. Masaryka 5555, 760 01 Zlin, Czech Republic. bunkova@ft.utb.cz.
773    0_
$w MED00180394 $t Molecules (Basel, Switzerland) $x 1420-3049 $g Roč. 22, č. 5 (2017)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/28448475 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20171025 $b ABA008
991    __
$a 20171030134240 $b ABA008
999    __
$a ok $b bmc $g 1254448 $s 991882
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2017 $b 22 $c 5 $e 20170427 $i 1420-3049 $m Molecules $n Molecules $x MED00180394
LZP    __
$a Pubmed-20171025

Find record

Citation metrics

Archiving options