Serum peptides derived from certain cleaved COMPLEMENT PROTEINS during COMPLEMENT ACTIVATION. They induce smooth MUSCLE CONTRACTION; mast cell HISTAMINE RELEASE; PLATELET AGGREGATION; and act as mediators of the local inflammatory process. The order of anaphylatoxin activity from the strongest to the weakest is C5a, C3a, C4a, and C5a des-arginine.

DUI

D000706 MeSH Browser

CUI

M0001074

Previous indexing

Peptides (1966-1976); Complement (1968-1976); Peptide Fragments (1974-1976); specific complement (1975-1976)

History note

90(77); was see under PEPTIDES 1977-89

Public note

90; was see under PEPTIDES 1977-89