Complement Membrane Attack Complex [membranolytický komplex]
- Terms
-
komplement - komplex C5b-9
komplement - komplex spojení s membránou
membránový lytický komplex
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C 5b-9
C5b-8-poly-C9
C5b-9
Complement Complex C5b-9
Cytolytic Terminal Complement Complex
Membrane Attack Complex
Terminal Complement Complex
A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the membrane attack complex or MAC.
- DUI
- D015938 MeSH Browser
- CUI
- M0024383
- Previous indexing
- Complement (1973-1989)
- History note
- 90
- Public note
- 90
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
SC5b-9 protein complex Chemical MeSH Browser