komplement C1 [Complement C1]

tematický
10
Termíny

komplement 1

 

C1 Complement
Complement 1
Complement Component 1

Perzistentní odkaz   https://www.medvik.cz/link/D003172
Definice

The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION.

Anotace
/antag permitted but consider also COMPLEMENT C1 INACTIVATOR PROTEINS
DUI
D003172 MeSH Prohlížeč
CUI
M0004924
Předchozí užití
Calcium (1966-1974); Complement (1968-1974)
Historická pozn.
2006 (1975)
Veřejná pozn.
2006; see COMPLEMENT 1 1978-2005, see COMPLEMENT 1975-1977

D Chemikálie a léčiva
D09 sacharidy 723
D10 lipidy 2 523
D12.776 proteiny 2 575
D12.776.124 krevní proteiny 909
D12.776.124.486 imunoproteiny 14
D12.776.124.486.274 komplement 350
D12.776.124.486.274.024 anafylatoxiny 6
D12.776.124.486.274.045 enzymy aktivující komplement 3
D12.776.124.486.274.050 komplement C1 10
D12.776.124.486.274.050.270 komplement C1q 23
D12.776.124.486.274.050.280 komplement C1r 1
D12.776.124.486.274.050.290 komplement C1s 4
D12.776.124.486.274.150 komplement C2 5
D12.776.124.486.274.250 komplement C3 40
D12.776.124.486.274.350 komplement 4 22
D12.776.124.486.274.450 komplement C5 26
D12.776.124.486.274.550 komplement C6
D12.776.124.486.274.650 komplement C7
D12.776.124.486.274.750 komplement C8 1
D12.776.124.486.274.850 komplement C9
D12.776.124.486.274.900 komplement - faktor B 3
D12.776.124.486.274.920 inaktivátory komplementu 20
D12.776.124.486.274.930 membranolytický komplex 4
D12.776.124.486.274.965 properdin 22