Complement C1 [komplement C1]
topical
10
- Terms
-
komplement 1
-
C1 Complement
Complement 1
Complement Component 1
Persistent link
https://www.medvik.cz/link/D003172
Definition
The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION.
- Annotation
- /antag permitted but consider also COMPLEMENT C1 INACTIVATOR PROTEINS
- DUI
- D003172 MeSH Browser
- CUI
- M0004924
- Previous indexing
- Calcium (1966-1974); Complement (1968-1974)
- History note
- 2006 (1975)
- Public note
- 2006; see COMPLEMENT 1 1978-2005, see COMPLEMENT 1975-1977
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors 3
- BI
- biosynthesis 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency 2
- DE
- drug effects
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology 4
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.776.124.486.274.550
Complement C6
D12.776.124.486.274.650
Complement C7
D12.776.124.486.274.850
Complement C9
C1qL4 protein, mouse Chemical MeSH Browser