-
Je něco špatně v tomto záznamu ?
Strategies for new and improved vaccines against ticks and tick-borne diseases
J. de la Fuente, P. Kopáček, A. Lew-Tabor, C. Maritz-Olivier,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, přehledy
NLK
Free Medical Journals
od 1997 do Před 1 rokem
Medline Complete (EBSCOhost)
od 1998-01-01 do Před 1 rokem
Wiley Free Content
od 1997 do Před 1 rokem
PubMed
27203187
DOI
10.1111/pim.12339
Knihovny.cz E-zdroje
- MeSH
- antigeny imunologie MeSH
- infestace klíšťaty parazitologie prevence a kontrola MeSH
- interakce hostitele a patogenu MeSH
- klíšťata imunologie MeSH
- lidé MeSH
- nemoci přenášené klíšťaty parazitologie prevence a kontrola MeSH
- vakcíny imunologie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Ticks infest a variety of animal species and transmit pathogens causing disease in both humans and animals worldwide. Tick-host-pathogen interactions have evolved through dynamic processes that accommodated the genetic traits of the hosts, pathogens transmitted and the vector tick species that mediate their development and survival. New approaches for tick control are dependent on defining molecular interactions between hosts, ticks and pathogens to allow for discovery of key molecules that could be tested in vaccines or new generation therapeutics for intervention of tick-pathogen cycles. Currently, tick vaccines constitute an effective and environmentally sound approach for the control of ticks and the transmission of the associated tick-borne diseases. New candidate protective antigens will most likely be identified by focusing on proteins with relevant biological function in the feeding, reproduction, development, immune response, subversion of host immunity of the tick vector and/or molecules vital for pathogen infection and transmission. This review addresses different approaches and strategies used for the discovery of protective antigens, including focusing on relevant tick biological functions and proteins, reverse genetics, vaccinomics and tick protein evolution and interactomics. New and improved tick vaccines will most likely contain multiple antigens to control tick infestations and pathogen infection and transmission.
- 000
- 00000naa a2200000 a 4500
- 001
- bmc17031725
- 003
- CZ-PrNML
- 005
- 20171101110520.0
- 007
- ta
- 008
- 171025s2016 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1111/pim.12339 $2 doi
- 035 __
- $a (PubMed)27203187
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a de la Fuente, J $u SaBio, Instituto de Investigación en Recursos Cinegéticos IREC (CSIC-UCLM-JCCM), Ciudad Real, Spain. Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK, USA.
- 245 10
- $a Strategies for new and improved vaccines against ticks and tick-borne diseases / $c J. de la Fuente, P. Kopáček, A. Lew-Tabor, C. Maritz-Olivier,
- 520 9_
- $a Ticks infest a variety of animal species and transmit pathogens causing disease in both humans and animals worldwide. Tick-host-pathogen interactions have evolved through dynamic processes that accommodated the genetic traits of the hosts, pathogens transmitted and the vector tick species that mediate their development and survival. New approaches for tick control are dependent on defining molecular interactions between hosts, ticks and pathogens to allow for discovery of key molecules that could be tested in vaccines or new generation therapeutics for intervention of tick-pathogen cycles. Currently, tick vaccines constitute an effective and environmentally sound approach for the control of ticks and the transmission of the associated tick-borne diseases. New candidate protective antigens will most likely be identified by focusing on proteins with relevant biological function in the feeding, reproduction, development, immune response, subversion of host immunity of the tick vector and/or molecules vital for pathogen infection and transmission. This review addresses different approaches and strategies used for the discovery of protective antigens, including focusing on relevant tick biological functions and proteins, reverse genetics, vaccinomics and tick protein evolution and interactomics. New and improved tick vaccines will most likely contain multiple antigens to control tick infestations and pathogen infection and transmission.
- 650 _2
- $a zvířata $7 D000818
- 650 _2
- $a antigeny $x imunologie $7 D000941
- 650 _2
- $a interakce hostitele a patogenu $7 D054884
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a infestace klíšťaty $x parazitologie $x prevence a kontrola $7 D013984
- 650 _2
- $a nemoci přenášené klíšťaty $x parazitologie $x prevence a kontrola $7 D017282
- 650 _2
- $a klíšťata $x imunologie $7 D013987
- 650 _2
- $a vakcíny $x imunologie $7 D014612
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a přehledy $7 D016454
- 700 1_
- $a Kopáček, P $u Institute of Parasitology, Biology Centre Czech Academy of Sciences, Ceske Budejovice, Czech Republic.
- 700 1_
- $a Lew-Tabor, A $u Queensland Alliance for Agriculture & Food Innovation, The University of Queensland, St. Lucia, Qld, Australia. Centre for Comparative Genomics, Murdoch University, Perth, WA, Australia.
- 700 1_
- $a Maritz-Olivier, C $u Department of Genetics, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africa.
- 773 0_
- $w MED00003687 $t Parasite immunology $x 1365-3024 $g Roč. 38, č. 12 (2016), s. 754-769
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/27203187 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20171025 $b ABA008
- 991 __
- $a 20171101110612 $b ABA008
- 999 __
- $a ok $b bmc $g 1255318 $s 992752
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2016 $b 38 $c 12 $d 754-769 $e 20160613 $i 1365-3024 $m Parasite immunology $n Parasite Immunol $x MED00003687
- LZP __
- $a Pubmed-20171025
