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Methodological standards for in vitro models of epilepsy and epileptic seizures. A TASK1-WG4 report of the AES/ILAE Translational Task Force of the ILAE

JV. Raimondo, U. Heinemann, M. de Curtis, HP. Goodkin, CG. Dulla, D. Janigro, A. Ikeda, CK. Lin, P. Jiruska, AS. Galanopoulou, C. Bernard,

. 2017 ; 58 Suppl 4 (-) : 40-52.

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, přehledy, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S., práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc18016242

Grantová podpora
NV15-29835A MZ0 CEP - Centrální evidence projektů

Digitální knihovna NLK
Plný text - Článek
Zdroj

E-zdroje Online Plný text

NLK Free Medical Journals od 1997 do Před 1 rokem
Wiley Free Content od 1997 do Před 4 lety

Odkazy

PubMed 29105075
DOI 10.1111/epi.13901
Knihovny.cz E-zdroje

In vitro preparations are a powerful tool to explore the mechanisms and processes underlying epileptogenesis and ictogenesis. In this review, we critically review the numerous in vitro methodologies utilized in epilepsy research. We provide support for the inclusion of detailed descriptions of techniques, including often ignored parameters with unpredictable yet significant effects on study reproducibility and outcomes. In addition, we explore how recent developments in brain slice preparation relate to their use as models of epileptic activity.

Citace poskytuje Crossref.org

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