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Progress in biocatalysis with immobilized viable whole cells: systems development, reaction engineering and applications
M. Polakovič, J. Švitel, M. Bučko, J. Filip, V. Neděla, MB. Ansorge-Schumacher, P. Gemeiner,
Language English Country Netherlands
Document type Journal Article, Review
NLK
ProQuest Central
from 1997-02-01 to 2017-12-31
Medline Complete (EBSCOhost)
from 2000-01-01 to 1 year ago
Health & Medicine (ProQuest)
from 1997-02-01 to 2017-12-31
- MeSH
- Bioengineering * MeSH
- Biocatalysis * MeSH
- Bioreactors * MeSH
- Cells, Immobilized * MeSH
- Humans MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Viable microbial cells are important biocatalysts in the production of fine chemicals and biofuels, in environmental applications and also in emerging applications such as biosensors or medicine. Their increasing significance is driven mainly by the intensive development of high performance recombinant strains supplying multienzyme cascade reaction pathways, and by advances in preservation of the native state and stability of whole-cell biocatalysts throughout their application. In many cases, the stability and performance of whole-cell biocatalysts can be highly improved by controlled immobilization techniques. This review summarizes the current progress in the development of immobilized whole-cell biocatalysts, the immobilization methods as well as in the bioreaction engineering aspects and economical aspects of their biocatalytic applications.
Center for Advanced Materials Qatar University Doha Qatar
Institute for Microbiology Faculty of Science Technische Universität Dresden Dresden Germany
Institute of Scientific Instruments Academy of Sciences Czech Republic Brno Czech Republic
References provided by Crossref.org
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- $a Viable microbial cells are important biocatalysts in the production of fine chemicals and biofuels, in environmental applications and also in emerging applications such as biosensors or medicine. Their increasing significance is driven mainly by the intensive development of high performance recombinant strains supplying multienzyme cascade reaction pathways, and by advances in preservation of the native state and stability of whole-cell biocatalysts throughout their application. In many cases, the stability and performance of whole-cell biocatalysts can be highly improved by controlled immobilization techniques. This review summarizes the current progress in the development of immobilized whole-cell biocatalysts, the immobilization methods as well as in the bioreaction engineering aspects and economical aspects of their biocatalytic applications.
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