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Progress in biocatalysis with immobilized viable whole cells: systems development, reaction engineering and applications

M. Polakovič, J. Švitel, M. Bučko, J. Filip, V. Neděla, MB. Ansorge-Schumacher, P. Gemeiner,

. 2017 ; 39 (5) : 667-683. [pub] 20170208

Jazyk angličtina Země Nizozemsko

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc18016776

E-zdroje NLK Online Plný text

ProQuest Central od 1997-02-01 do Před 1 rokem
Medline Complete (EBSCOhost) od 2000-01-01 do Před 1 rokem
Health & Medicine (ProQuest) od 1997-02-01 do Před 1 rokem

Viable microbial cells are important biocatalysts in the production of fine chemicals and biofuels, in environmental applications and also in emerging applications such as biosensors or medicine. Their increasing significance is driven mainly by the intensive development of high performance recombinant strains supplying multienzyme cascade reaction pathways, and by advances in preservation of the native state and stability of whole-cell biocatalysts throughout their application. In many cases, the stability and performance of whole-cell biocatalysts can be highly improved by controlled immobilization techniques. This review summarizes the current progress in the development of immobilized whole-cell biocatalysts, the immobilization methods as well as in the bioreaction engineering aspects and economical aspects of their biocatalytic applications.

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$a Neděla, Vilém $u Institute of Scientific Instruments, Academy of Sciences Czech Republic, Brno, Czech Republic.
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$a Ansorge-Schumacher, Marion B $u Institute for Microbiology, Faculty of Science, Technische Universität Dresden, Dresden, Germany.
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