• Je něco špatně v tomto záznamu ?

Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1

C. Deloizy, E. Bouguyon, E. Fossum, P. Sebo, R. Osicka, A. Bole, M. Pierres, S. Biacchesi, M. Dalod, B. Bogen, N. Bertho, I. Schwartz-Cornil,

. 2016 ; 65 (-) : 31-40. [pub] 20160621

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc18017185

Pig is a domestic species of major importance in the agro-economy and in biomedical research. Mononuclear phagocytes (MNP) are organized in subsets with specialized roles in the orchestration of the immune response and new tools are awaited to improve MNP subset identification in the pig. We cloned pig CD11c cDNA and generated a monoclonal antibody to pig CD11c which showed a pattern of expression by blood and skin MNP subsets similar to humans. We also developed a porcine XCL1-mCherry dimer which specifically reacted with the XCR1-expressing dendritic cell subset of the type 1 lineage in blood and skin. These original reagents will allow the efficient identification of pig MNP subsets to study their role in physiological and pathological processes and also to target these cells in novel intervention and vaccine strategies for veterinary applications and preclinical evaluations.

000      
00000naa a2200000 a 4500
001      
bmc18017185
003      
CZ-PrNML
005      
20180523094035.0
007      
ta
008      
180515s2016 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.dci.2016.06.015 $2 doi
035    __
$a (PubMed)27345169
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Deloizy, Charlotte $u VIM-INRA-Université Paris-Saclay, Domaine de Vilvert, 78350, Jouy-en-Josas, France.
245    10
$a Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1 / $c C. Deloizy, E. Bouguyon, E. Fossum, P. Sebo, R. Osicka, A. Bole, M. Pierres, S. Biacchesi, M. Dalod, B. Bogen, N. Bertho, I. Schwartz-Cornil,
520    9_
$a Pig is a domestic species of major importance in the agro-economy and in biomedical research. Mononuclear phagocytes (MNP) are organized in subsets with specialized roles in the orchestration of the immune response and new tools are awaited to improve MNP subset identification in the pig. We cloned pig CD11c cDNA and generated a monoclonal antibody to pig CD11c which showed a pattern of expression by blood and skin MNP subsets similar to humans. We also developed a porcine XCL1-mCherry dimer which specifically reacted with the XCR1-expressing dendritic cell subset of the type 1 lineage in blood and skin. These original reagents will allow the efficient identification of pig MNP subsets to study their role in physiological and pathological processes and also to target these cells in novel intervention and vaccine strategies for veterinary applications and preclinical evaluations.
650    _2
$a zvířata $7 D000818
650    _2
$a monoklonální protilátky $x metabolismus $7 D000911
650    _2
$a antigeny CD11c $x imunologie $x metabolismus $7 D039521
650    _2
$a klonování DNA $7 D003001
650    _2
$a dendritické buňky $x fyziologie $7 D003713
650    _2
$a modely nemocí na zvířatech $7 D004195
650    _2
$a lidé $7 D006801
650    _2
$a imunologické testy $x metody $7 D007159
650    12
$a mononukleární fagocytární systém $7 D012157
650    _2
$a fagocyty $x imunologie $7 D010586
650    _2
$a receptory spřažené s G-proteiny $x imunologie $x metabolismus $7 D043562
650    _2
$a kůže $x metabolismus $7 D012867
650    _2
$a prasata $x imunologie $7 D013552
650    _2
$a veterinární lékařství $7 D014730
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Bouguyon, Edwige $u VIM-INRA-Université Paris-Saclay, Domaine de Vilvert, 78350, Jouy-en-Josas, France.
700    1_
$a Fossum, Even $u K.G. Jebsen Center for Research on Influenza Vaccines, University of Oslo and Oslo University Hospital, 0027, Oslo, Norway.
700    1_
$a Sebo, Peter $u Institute of Microbiology of the Czech Academy of Sciences, v.v.i., 142 20, Prague, Czech Republic.
700    1_
$a Osicka, Radim $u Institute of Microbiology of the Czech Academy of Sciences, v.v.i., 142 20, Prague, Czech Republic.
700    1_
$a Bole, Angélique $u MI-mAbs, Parc Scientifique et Technologique de Luminy, Case 906, F13288, Marseille Cedex 9, France.
700    1_
$a Pierres, Michel $u MI-mAbs, Parc Scientifique et Technologique de Luminy, Case 906, F13288, Marseille Cedex 9, France.
700    1_
$a Biacchesi, Stéphane $u VIM-INRA-Université Paris-Saclay, Domaine de Vilvert, 78350, Jouy-en-Josas, France.
700    1_
$a Dalod, Marc $u Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université UM2, Inserm, U1104, CNRS UMR7280, 13288, Marseille, France.
700    1_
$a Bogen, Bjarne $u K.G. Jebsen Center for Research on Influenza Vaccines, University of Oslo and Oslo University Hospital, 0027, Oslo, Norway; Center for Immune Regulation, Institute of Immunology, University of Oslo and Oslo University Hospital Rikshospitalet, 0424, Oslo, Norway.
700    1_
$a Bertho, Nicolas $u VIM-INRA-Université Paris-Saclay, Domaine de Vilvert, 78350, Jouy-en-Josas, France.
700    1_
$a Schwartz-Cornil, Isabelle $u VIM-INRA-Université Paris-Saclay, Domaine de Vilvert, 78350, Jouy-en-Josas, France. Electronic address: isabelle.schwartz@jouy.inra.fr.
773    0_
$w MED00001364 $t Developmental and comparative immunology $x 1879-0089 $g Roč. 65, č. - (2016), s. 31-40
856    41
$u https://pubmed.ncbi.nlm.nih.gov/27345169 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20180515 $b ABA008
991    __
$a 20180523094219 $b ABA008
999    __
$a ok $b bmc $g 1300809 $s 1014025
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2016 $b 65 $c - $d 31-40 $e 20160621 $i 1879-0089 $m Developmental and comparative immunology $n Dev Comp Immunol $x MED00001364
LZP    __
$a Pubmed-20180515

Najít záznam

Citační ukazatele

Možnosti archivace