Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Moderate exercise based on artificial gravity preserves orthostatic tolerance and exercise capacity during short-term head-down bed rest

X. T. Li, C. B. Yang, Y. S. Zhu, J. Sun, F. Shi, Y. C. Wang, Y. Gao, J. D. Zhao, X. Q. Sun

. 2017 ; 66 (4) : 567-580. [pub] 20170412

Language English Country Czech Republic

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc18021061

Numerous countermeasures have been proposed to minimize microgravity-induced physical deconditioning, but their benefits are limited. The present study aimed to investigate whether personalized aerobic exercise based on artificial gravity (AG) mitigates multisystem physical deconditioning. Fourteen men were assigned to the control group (n=6) and the countermeasure group (CM, n=8). Subjects in the CM group were exposed to AG (2 Gz at foot level) for 30 min twice daily, during which time cycling exercise of 80-95 % anaerobic threshold (AT) intensity was undertaken. Orthostatic tolerance (OT), exercise tests, and blood assays were determined before and after 4 days head-down bed rest (HDBR). Cardiac systolic function was measured every day. After HDBR, OT decreased to 50.9 % and 77.5 % of pre-HDBR values in control and CM groups, respectively. Exercise endurance, maximal oxygen consumption, and AT decreased to 96.5 %, 91.5 % and 91.8 % of pre-HDBR values, respectively, in the control group. Nevertheless, there were slight changes in the CM group. HDBR increased heart rate, sympathetic activity, and the pre-ejection period, but decreased plasma volume, parasympathetic activity and left-ventricular ejection time in the control group, whereas these effects were eliminated in the CM group. Aldosterone had no change in the control group but increased significantly in the CM group. Our study shows that 80-95 % AT aerobic exercise based on 2 Gz of AG preserves OT and exercise endurance, and affects body fluid regulation during short-term HDBR. The underlying mechanisms might involve maintained cardiac systolic function, preserved plasma volume, and improved sympathetic responses to orthostatic stress.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc18021061
003      
CZ-PrNML
005      
20180621135910.0
007      
ta
008      
180611s2017 xr d f 000 0|eng||
009      
AR
024    7_
$a 10.33549/physiolres.933493 $2 doi
035    __
$a (PubMed)28406700
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Li, Xiao-Tao $u Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China; Department of Physical Education and Exercise Science, Xidian University, Xi'an, China
245    10
$a Moderate exercise based on artificial gravity preserves orthostatic tolerance and exercise capacity during short-term head-down bed rest / $c X. T. Li, C. B. Yang, Y. S. Zhu, J. Sun, F. Shi, Y. C. Wang, Y. Gao, J. D. Zhao, X. Q. Sun
520    9_
$a Numerous countermeasures have been proposed to minimize microgravity-induced physical deconditioning, but their benefits are limited. The present study aimed to investigate whether personalized aerobic exercise based on artificial gravity (AG) mitigates multisystem physical deconditioning. Fourteen men were assigned to the control group (n=6) and the countermeasure group (CM, n=8). Subjects in the CM group were exposed to AG (2 Gz at foot level) for 30 min twice daily, during which time cycling exercise of 80-95 % anaerobic threshold (AT) intensity was undertaken. Orthostatic tolerance (OT), exercise tests, and blood assays were determined before and after 4 days head-down bed rest (HDBR). Cardiac systolic function was measured every day. After HDBR, OT decreased to 50.9 % and 77.5 % of pre-HDBR values in control and CM groups, respectively. Exercise endurance, maximal oxygen consumption, and AT decreased to 96.5 %, 91.5 % and 91.8 % of pre-HDBR values, respectively, in the control group. Nevertheless, there were slight changes in the CM group. HDBR increased heart rate, sympathetic activity, and the pre-ejection period, but decreased plasma volume, parasympathetic activity and left-ventricular ejection time in the control group, whereas these effects were eliminated in the CM group. Aldosterone had no change in the control group but increased significantly in the CM group. Our study shows that 80-95 % AT aerobic exercise based on 2 Gz of AG preserves OT and exercise endurance, and affects body fluid regulation during short-term HDBR. The underlying mechanisms might involve maintained cardiac systolic function, preserved plasma volume, and improved sympathetic responses to orthostatic stress.
650    _2
$a dospělí $7 D000328
650    _2
$a klid na lůžku $x metody $7 D001510
650    _2
$a krevní tlak $x fyziologie $7 D001794
650    _2
$a cvičení $x fyziologie $7 D015444
650    12
$a gravitace změněná $7 D018470
650    _2
$a Trendelenburgova poloha $x fyziologie $7 D018475
650    _2
$a srdeční frekvence $x fyziologie $7 D006339
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a ortostatická intolerance $x diagnóza $x patofyziologie $7 D054971
650    _2
$a spotřeba kyslíku $x fyziologie $7 D010101
650    _2
$a časové faktory $7 D013997
650    _2
$a simulace stavu beztíže $x metody $7 D018474
650    _2
$a mladý dospělý $7 D055815
655    _2
$a časopisecké články $7 D016428
700    1_
$a Yang, Chang-Bin $u Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China
700    1_
$a Zhu, Yong-Sheng $u Department of Ultrasound Diagnosis, Xijing Hospital, Fourth Military Medical University, Xi'an, China
700    1_
$a Sun, Jing $u Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China
700    1_
$a Shi, Fei $u Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China
700    1_
$a Wang, Yong-Chun $u Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China
700    1_
$a Gao, Yuan $u Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China
700    1_
$a Zhao, Jiang-Dong $u Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China
700    1_
$a Sun, Xi-Qing $u Department of Aerospace Biodynamics, Faculty of Aerospace Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China
773    0_
$w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 66, č. 4 (2017), s. 567-580
856    41
$u https://pubmed.ncbi.nlm.nih.gov/28406700 $y Pubmed
910    __
$a ABA008 $b A 4120 $c 266 $y 4 $z 0
990    __
$a 20180611 $b ABA008
991    __
$a 20180619092038 $b ABA008
999    __
$a ok $b bmc $g 1311775 $s 1017933
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2017 $b 66 $c 4 $d 567-580 $e 20170412 $i 1802-9973 $m Physiological research $n Physiol. Res. (Print) $x MED00003824
LZP    __
$b NLK118 $a Pubmed-20180611

Find record

Citation metrics

Archiving options