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Cytokinin signalling regulates organ identity via the AHK4 receptor in Arabidopsis

M. Pernisova, M. Grochova, T. Konecny, L. Plackova, D. Harustiakova, T. Kakimoto, MG. Heisler, O. Novak, J. Hejatko,

. 2018 ; 145 (14) : . [pub] 20180720

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc18033021
E-zdroje Online Plný text

NLK Free Medical Journals od 1953 do Před 6 měsíci
Open Access Digital Library od 1953-03-01 do Před 6 měsíci

Odkazy

PubMed 29967282
DOI 10.1242/dev.163907
Knihovny.cz E-zdroje

Mutual interactions of the phytohormones, cytokinins and auxin determine root or shoot identity during postembryonic de novo organogenesis in plants. However, our understanding of the role of hormonal metabolism and perception during early stages of cell fate reprogramming is still elusive. Here we show that auxin activates root formation, whereas cytokinins mediate early loss of the root identity, primordia disorganisation and initiation of shoot development. Exogenous and endogenous cytokinins influence the initiation of newly formed organs, as well as the pace of organ development. The process of de novo shoot apical meristem establishment is accompanied by accumulation of endogenous cytokinins, differential regulation of genes for individual cytokinin receptors, strong activation of AHK4-mediated signalling and induction of the shoot-specific homeodomain regulator WUSCHEL. The last is associated with upregulation of isopentenyladenine-type cytokinins, revealing higher shoot-forming potential when compared with trans-zeatin. Moreover, AHK4-controlled cytokinin signalling negatively regulates the root stem cell organiser WUSCHEL RELATED HOMEOBOX 5 in the root quiescent centre. We propose an important role for endogenous cytokinin biosynthesis and AHK4-mediated cytokinin signalling in the control of de novo-induced organ identity.

Citace poskytuje Crossref.org

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