• Je něco špatně v tomto záznamu ?

Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research

A. Kapinova, P. Stefanicka, P. Kubatka, P. Zubor, S. Uramova, M. Kello, J. Mojzis, D. Blahutova, T. Qaradakhi, A. Zulli, M. Caprnda, J. Danko, Z. Lasabova, D. Busselberg, P. Kruzliak,

. 2017 ; 96 (-) : 1465-1477. [pub] 20171201

Jazyk angličtina Země Francie

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc18033492

Breast cancer is the most common malignancy in women worldwide. Over 90% of all breast cancer cases are of different 'sporadic' cell types, thus placing emphasis on the need for breast cancer prevention and new effective treatment strategies. In recent years, pre-clinical research provides growing evidence regarding the beneficial action of bioactive plant-derived substances - phytochemicals, on multiple cancer-related biological pathways. The important natural source of various phytochemicals with anti-oncogenic properties are plant-based functional foods. It is hypothesized that a significant anti-tumour activity of plant-based functional foods are the result of a combination of various phytochemicals rather than an isolated agent. The mixture of phytochemicals with various biological activities present in whole foods could have additive or synergistic effects against carcinogenesis. Clinically, it is very important to compare the effect of the isolated phytochemicals against the mixture of phytochemicals present in specific plant-based functional foods. Therefore, the purpose of this review article is to compare anticancer activities of isolated phytochemicals and plant-based functional foods for the prevention and therapy of breast carcinoma. Our conclusion supports the hypothesis that a mixture of wide range of phytochemicals with a plethora of biological activities present in whole plant-derived foods could have additive or synergistic effects against breast cancer. Although, the lack of parallel comparative studies between whole natural foods versus isolated plant compounds limits our conclusion, future pre-clinical and clinical studies evaluating this issue is required.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc18033492
003      
CZ-PrNML
005      
20210219152708.0
007      
ta
008      
181008s2017 fr f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.biopha.2017.11.134 $2 doi
035    __
$a (PubMed)29198744
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a fr
100    1_
$a Kapinova, Andrea $u Division of Oncology, Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University, Martin, Slovakia.
245    10
$a Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research / $c A. Kapinova, P. Stefanicka, P. Kubatka, P. Zubor, S. Uramova, M. Kello, J. Mojzis, D. Blahutova, T. Qaradakhi, A. Zulli, M. Caprnda, J. Danko, Z. Lasabova, D. Busselberg, P. Kruzliak,
520    9_
$a Breast cancer is the most common malignancy in women worldwide. Over 90% of all breast cancer cases are of different 'sporadic' cell types, thus placing emphasis on the need for breast cancer prevention and new effective treatment strategies. In recent years, pre-clinical research provides growing evidence regarding the beneficial action of bioactive plant-derived substances - phytochemicals, on multiple cancer-related biological pathways. The important natural source of various phytochemicals with anti-oncogenic properties are plant-based functional foods. It is hypothesized that a significant anti-tumour activity of plant-based functional foods are the result of a combination of various phytochemicals rather than an isolated agent. The mixture of phytochemicals with various biological activities present in whole foods could have additive or synergistic effects against carcinogenesis. Clinically, it is very important to compare the effect of the isolated phytochemicals against the mixture of phytochemicals present in specific plant-based functional foods. Therefore, the purpose of this review article is to compare anticancer activities of isolated phytochemicals and plant-based functional foods for the prevention and therapy of breast carcinoma. Our conclusion supports the hypothesis that a mixture of wide range of phytochemicals with a plethora of biological activities present in whole plant-derived foods could have additive or synergistic effects against breast cancer. Although, the lack of parallel comparative studies between whole natural foods versus isolated plant compounds limits our conclusion, future pre-clinical and clinical studies evaluating this issue is required.
650    _2
$a zvířata $7 D000818
650    _2
$a antitumorózní látky $x farmakologie $x terapeutické užití $7 D000970
650    _2
$a nádory prsu $x farmakoterapie $7 D001943
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a funkční potraviny $7 D055951
650    _2
$a lidé $7 D006801
650    _2
$a fytonutrienty $x farmakologie $x terapeutické užití $7 D064209
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Stefanicka, Patrik $u Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
700    1_
$a Kubatka, Peter $u Division of Oncology, Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University, Martin, Slovakia; Department of Medical Biology, Jessenius Faculty of Medicine in Martin, Comenius University, Martin, Slovakia. Electronic address: kubatka@jfmed.uniba.sk.
700    1_
$a Žúbor, Pavol, $d 1975- $u Department of Obstetrics and Gynecology, Jessenius Faculty of Medicine in Martin Comenius University, Slovakia. $7 xx0117542
700    1_
$a Uramova, Sona $u Department of Obstetrics and Gynecology, Jessenius Faculty of Medicine in Martin Comenius University, Slovakia.
700    1_
$a Kello, Martin $u Department of Pharmacology, Faculty of Medicine, Pavol Jozef Safarik University, Kosice, Slovakia.
700    1_
$a Mojzis, Jan $u Department of Pharmacology, Faculty of Medicine, Pavol Jozef Safarik University, Kosice, Slovakia.
700    1_
$a Blahutova, Dana $u Department of Biology and Ecology, Faculty of Education, Catholic University in Ruzomberok, Ruzomberok, Slovakia.
700    1_
$a Qaradakhi, Tawar $u The Centre for Chronic Disease, College of Health & Biomedicine, Victoria University, Melbourne, Werribee Campus, Victoria, Australia.
700    1_
$a Zulli, Anthony $u The Centre for Chronic Disease, College of Health & Biomedicine, Victoria University, Melbourne, Werribee Campus, Victoria, Australia.
700    1_
$a Caprnda, Martin $u 1st Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
700    1_
$a Danko, Jan $u Department of Obstetrics and Gynecology, Jessenius Faculty of Medicine in Martin Comenius University, Slovakia.
700    1_
$a Lasabova, Zora $u Division of Oncology, Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University, Martin, Slovakia.
700    1_
$a Busselberg, Dietrich $u Weill Cornell Medicine in Qatar, Qatar Foundation-Education City, Doha, Qatar.
700    1_
$a Kruzliak, Peter $u Department of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic. Electronic address: kruzliakpeter@gmail.com.
773    0_
$w MED00005486 $t Biomedicine & pharmacotherapy Biomedecine & pharmacotherapie $x 1950-6007 $g Roč. 96, č. - (2017), s. 1465-1477
856    41
$u https://pubmed.ncbi.nlm.nih.gov/29198744 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20181008 $b ABA008
991    __
$a 20210219152706 $b ABA008
999    __
$a ok $b bmc $g 1340173 $s 1030486
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2017 $b 96 $c - $d 1465-1477 $e 20171201 $i 1950-6007 $m Biomedicine & pharmacotherapy $n Biomed Pharmacother $x MED00005486
LZP    __
$a Pubmed-20181008

Najít záznam

Citační ukazatele

Možnosti archivace