• Something wrong with this record ?

Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors

L. Minar, M. Felsinger, Z. Cermakova, F. Zlamal, J. Bienertova-Vasku,

. 2018 ; 140 (2) : 241-246. [pub] 20171122

Language English Country United States

Document type Comparative Study, Journal Article

Persistent link   https://www.medvik.cz/link/bmc18033613

OBJECTIVE: To compare the Copenhagen Index (CPH-I) and the Risk of Ovarian Malignancy Algorithm (ROMA) in the differential diagnosis of ovarian tumors. METHODS: In a retrospective study, data were reviewed from women with ovarian tumors who attended University Hospital Brno, Czech Republic, between July 2011 and June 2015. The women were classified into the benign tumor group or malignant tumor group (borderline and malignant tumors). Serum levels of CA125 and HE4 were extracted from medical records. The two tumor indices were calculated using relevant clinical data. RESULTS: Among 267 included women, 110 had benign tumors, 42 had borderline ovarian tumors, and 115 had malignant tumors. The two indices showed similar discriminatory performance with no significant differences (P>0.05). In the differentiation of benign tumors from all stages of borderline tumor and ovarian cancer, ROMA showed a sensitivity of 71% at a specificity of 88%, whereas CPH-I showed a sensitivity of 69% at a specificity of 85%. CONCLUSION: CPH-I is a potential tumor index that is independent of menopausal status. It might be applied as a simple alternative to ROMA in settings of basic medical care.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc18033613
003      
CZ-PrNML
005      
20181023105730.0
007      
ta
008      
181008s2018 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1002/ijgo.12371 $2 doi
035    __
$a (PubMed)29086914
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Minar, Lubos $u Department of Gynecology and Obstetrics, Faculty of Medicine, Masaryk University, Brno, Czech Republic. University Hospital Brno, Brno, Czech Republic.
245    10
$a Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors / $c L. Minar, M. Felsinger, Z. Cermakova, F. Zlamal, J. Bienertova-Vasku,
520    9_
$a OBJECTIVE: To compare the Copenhagen Index (CPH-I) and the Risk of Ovarian Malignancy Algorithm (ROMA) in the differential diagnosis of ovarian tumors. METHODS: In a retrospective study, data were reviewed from women with ovarian tumors who attended University Hospital Brno, Czech Republic, between July 2011 and June 2015. The women were classified into the benign tumor group or malignant tumor group (borderline and malignant tumors). Serum levels of CA125 and HE4 were extracted from medical records. The two tumor indices were calculated using relevant clinical data. RESULTS: Among 267 included women, 110 had benign tumors, 42 had borderline ovarian tumors, and 115 had malignant tumors. The two indices showed similar discriminatory performance with no significant differences (P>0.05). In the differentiation of benign tumors from all stages of borderline tumor and ovarian cancer, ROMA showed a sensitivity of 71% at a specificity of 88%, whereas CPH-I showed a sensitivity of 69% at a specificity of 85%. CONCLUSION: CPH-I is a potential tumor index that is independent of menopausal status. It might be applied as a simple alternative to ROMA in settings of basic medical care.
650    _2
$a dospělí $7 D000328
650    _2
$a senioři $7 D000368
650    12
$a algoritmy $7 D000465
650    _2
$a nádorové biomarkery $x krev $7 D014408
650    _2
$a antigen CA-125 $x krev $7 D018394
650    _2
$a Česká republika $7 D018153
650    _2
$a diferenciální diagnóza $7 D003937
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a lidé středního věku $7 D008875
650    _2
$a nádory vaječníků $x krev $x klasifikace $x diagnóza $x patologie $7 D010051
650    _2
$a retrospektivní studie $7 D012189
650    _2
$a riziko $7 D012306
650    _2
$a senzitivita a specificita $7 D012680
655    _2
$a srovnávací studie $7 D003160
655    _2
$a časopisecké články $7 D016428
700    1_
$a Felsinger, Michal $7 xx0228419 $u Department of Gynecology and Obstetrics, Faculty of Medicine, Masaryk University, Brno, Czech Republic. University Hospital Brno, Brno, Czech Republic.
700    1_
$a Cermakova, Zdenka $u Department of Biochemistry, University Hospital Brno, Brno, Czech Republic.
700    1_
$a Zlamal, Filip $u Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic. Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic.
700    1_
$a Bienertova-Vasku, Julie $u Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic. Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic.
773    0_
$w MED00009895 $t International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics $x 1879-3479 $g Roč. 140, č. 2 (2018), s. 241-246
856    41
$u https://pubmed.ncbi.nlm.nih.gov/29086914 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20181008 $b ABA008
991    __
$a 20181023110237 $b ABA008
999    __
$a ok $b bmc $g 1339525 $s 1030607
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 140 $c 2 $d 241-246 $e 20171122 $i 1879-3479 $m International journal of gynaecology and obstetrics $n Int J Gynaecol Obstet $x MED00009895
LZP    __
$a Pubmed-20181008
Back

Find record

Citation metrics

Archiving options