Zinc oxide (ZnO) nanoparticles (NPs) are a promising platform for use in biomedical research, especially given their anticancer and antimicrobial activities. These activities are associated with the ability of ZnO NPs to generate reactive oxygen species (ROS) and induce apoptosis. In addition, ZnO NPs have been successfully exploited as drug carriers for loading and transporting drugs to target sites, thereby reducing unwanted toxicity and off-target effects, and resulting in amplified synergistic effects. Here, we discuss the synthesis and biomedical applications of ZnO NPs.

Department of Pharmaceutics Jamia Hamdard New Delhi India

Department of Production Management and Engineering Warsaw University of Life Sciences Faculty of Production Engineering Warsaw Poland

Department of Wood Processing Mendel University in Brno Brno Czech Republic

School of Pharmacy Texas Tech University Health Sciences Center Amarillo TX USA

000      

00000naa a2200000 a 4500

001      

bmc18033760

003      

CZ-PrNML

005      

20181026101951.0

007      

ta

008      

181008s2017 enk f 000 0|eng||

009      

AR

024    7_

$a 10.1016/j.drudis.2017.08.006 $2 doi

035    __

$a (PubMed)28847758

040    __

$a ABA008 $b cze $d ABA008 $e AACR2

041    0_

$a eng

044    __

$a enk

100    1_

$a Mishra, Pawan K $u Department of Wood Processing, Mendel University in Brno, Brno, Czech Republic.

245    10

$a Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications / $c PK. Mishra, H. Mishra, A. Ekielski, S. Talegaonkar, B. Vaidya,

520    9_

$a Zinc oxide (ZnO) nanoparticles (NPs) are a promising platform for use in biomedical research, especially given their anticancer and antimicrobial activities. These activities are associated with the ability of ZnO NPs to generate reactive oxygen species (ROS) and induce apoptosis. In addition, ZnO NPs have been successfully exploited as drug carriers for loading and transporting drugs to target sites, thereby reducing unwanted toxicity and off-target effects, and resulting in amplified synergistic effects. Here, we discuss the synthesis and biomedical applications of ZnO NPs.

650    _2

$a zvířata $7 D000818

650    _2

$a lidé $7 D006801

650    12

$a nanočástice $x aplikace a dávkování $x chemie $7 D053758

650    12

$a oxid zinečnatý $x chemie $x farmakokinetika $x farmakologie $7 D015034

655    _2

$a časopisecké články $7 D016428

655    _2

$a přehledy $7 D016454

700    1_

$a Mishra, Harshita $u Department of Pharmaceutics, Jamia Hamdard, New Delhi, India.

700    1_

$a Ekielski, Adam $u Department of Production Management and Engineering, Warsaw University of Life Sciences, Faculty of Production Engineering, Warsaw, Poland.

700    1_

$a Talegaonkar, Sushama $u Department of Pharmaceutics, Jamia Hamdard, New Delhi, India.

700    1_

$a Vaidya, Bhuvaneshwar $u School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA. Electronic address: bhuvanvaidya@gmail.com.

773    0_

$w MED00173737 $t Drug discovery today $x 1878-5832 $g Roč. 22, č. 12 (2017), s. 1825-1834

856    41

$u https://pubmed.ncbi.nlm.nih.gov/28847758 $y Pubmed

910    __

$a ABA008 $b sig $c sign $y a $z 0

990    __

$a 20181008 $b ABA008

991    __

$a 20181026102502 $b ABA008

999    __

$a ok $b bmc $g 1340278 $s 1030754

BAS    __

$a 3

BAS    __

$a PreBMC

BMC    __

$a 2017 $b 22 $c 12 $d 1825-1834 $e 20170825 $i 1878-5832 $m Drug discovery today $n Drug Discov Today Dis Mech $x MED00173737

LZP    __

$a Pubmed-20181008