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The effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesters
J. Horakova, P. Mikes, A. Saman, V. Jencova, A. Klapstova, T. Svarcova, M. Ackermann, V. Novotny, T. Suchy, D. Lukas,
Materials science & engineering. C, Materials for biological applications.
2018 ;
92 (-) :
132-142.
[pub] 20180627
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články
Perzistentní odkaz
https://www.medvik.cz/link/bmc19000393
- MeSH
- biokompatibilní materiály chemie metabolismus farmakologie MeSH
- buněčné linie MeSH
- cévní protézy MeSH
- ethylenoxid chemie farmakologie MeSH
- mikroskopie elektronová rastrovací MeSH
- modul pružnosti MeSH
- myši MeSH
- nanovlákna chemie MeSH
- pevnost v tahu MeSH
- polyestery chemie metabolismus MeSH
- sterilizace MeSH
- viabilita buněk účinky léků MeSH
- zvířata MeSH
- Check Tag
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
The study describes the detailed examination of the effect of ethylene oxide sterilization on electrospun scaffolds constructed from biodegradable polyesters. Different fibrous layers fabricated from polycaprolactone (PCL) and a copolymer consisting of polylactide and polycaprolactone (PLCL) were investigated for the determination of their mechanical properties, degradation rates and interaction with fibroblasts. It was discovered that the sterilization procedure influenced the mechanical properties of the electrospun PLCL copolymer scaffold to the greatest extent. No effect of ethylene oxide sterilization on degradation behavior was observed. However, a delayed fibroblast proliferation rate was noticed with concern to the ethylene oxide sterilized samples compared to the ethanol sterilization of the materials.
Citace poskytuje Crossref.org
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- $a Horakova, J $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: jana.horakova@tul.cz.
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- $a The effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesters / $c J. Horakova, P. Mikes, A. Saman, V. Jencova, A. Klapstova, T. Svarcova, M. Ackermann, V. Novotny, T. Suchy, D. Lukas,
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- $a The study describes the detailed examination of the effect of ethylene oxide sterilization on electrospun scaffolds constructed from biodegradable polyesters. Different fibrous layers fabricated from polycaprolactone (PCL) and a copolymer consisting of polylactide and polycaprolactone (PLCL) were investigated for the determination of their mechanical properties, degradation rates and interaction with fibroblasts. It was discovered that the sterilization procedure influenced the mechanical properties of the electrospun PLCL copolymer scaffold to the greatest extent. No effect of ethylene oxide sterilization on degradation behavior was observed. However, a delayed fibroblast proliferation rate was noticed with concern to the ethylene oxide sterilized samples compared to the ethanol sterilization of the materials.
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- $a Mikes, P $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: petr.mikes@tul.cz.
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- $a Saman, A $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: ales.saman@tul.cz.
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- $a Jencova, V $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: vera.jencova@tul.cz.
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- $a Klapstova, A $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: andrea.klapstova@tul.cz.
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- $a Svarcova, T $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: tereza.svarcova@tul.cz.
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- $a Ackermann, M $u Department of Industrial Technology, Institute of Nanomaterials, Advanced Technologies and Innovation, Technical University of Liberec, Studentska 1402/2, 460 01 Liberec, Czech Republic. Electronic address: michal.ackermann@tul.cz.
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- $a Lukas, D $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic. Electronic address: david.lukas@tul.cz.
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