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Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block
A. Kučerová, P. Doškář, L. Dujka, V. Lekešová, P. Volf, K. Koščová, P. Neužil, F. Málek,
Language English Country England, Great Britain
Document type Case Reports, Journal Article
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Directory of Open Access Journals
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PubMed Central
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- MeSH
- Bundle-Branch Block complications diagnostic imaging drug therapy physiopathology MeSH
- Adult MeSH
- Electrocardiography MeSH
- Ivabradine pharmacology therapeutic use MeSH
- Cardiomyopathies complications diagnostic imaging drug therapy physiopathology MeSH
- Middle Aged MeSH
- Humans MeSH
- Atrial Remodeling drug effects MeSH
- Aged MeSH
- Heart Rate drug effects MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
Left bundle branch block increases the risk of death in patients with chronic heart failure. We herein report four clinical cases of patients with chronic heart failure caused by nonischemic cardiomyopathy with left bundle branch block that occurred when adding ivabradine to optimal medical therapy, resulting in reverse electrical and mechanical remodeling. This phenomenon might be explained by the effect of ivabradine on reverse remodeling of the left ventricle with improvement of intraventricular conduction.
References provided by Crossref.org
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