RNA-Binding Protein FUS [protein FUS vázající RNA]
- Terms
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RNA-vazebný protein FUS
RNA-vazebný protein regulující rekombinaci tvorby fúzních proteinů
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FUS Protein
FUS RNA-Binding Protein
Fusion Protein in Myxoid Liposarcoma
hnRNP P2
POMp75 Protein
TLS Protein
Translocated in Liposarcoma Protein
A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.
- DUI
- D034702 MeSH Browser
- CUI
- M0087111
- Previous indexing
- Ribonucleoproteins (1996-2002)
- History note
- 2003; for FUS PROTEIN & HNRNP P2 use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS (NM) 1996-2002; for TLS PROTEIN use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS (NM) 1993-2002;
- Public note
- 2003; FUS PROTEIN & HNRNP P2 were indexed under RIBONUCLEOPROTEINS 1996-2002; TLS PROTEIN was indexed under 1993-2002 RIBONUCLEOPROTEINS
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
FUS protein, human Chemical MeSH Browser
FUS protein, mouse Chemical MeSH Browser
FUST-1 protein, C elegans Chemical MeSH Browser
TLS-CHOP fusion protein, human Chemical MeSH Browser
TLS-ERG fusion protein, human Chemical MeSH Browser