nádorové proteiny [Neoplasm Proteins]
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
- Anotace
- IM & coord with specific protein (IM) + specific histol type (IM) + specific organ/neoplasms term (IM); Manual 24.4.4.4
- DUI
- D009363 MeSH Prohlížeč
- CUI
- M0014578
Povolená podhesla
- AG
- agonisté 1
- AN
- analýza 63
- AI
- antagonisté a inhibitory 26
- AD
- aplikace a dávkování 0
- BI
- biosyntéza 41
- CS
- chemická syntéza 0
- CH
- chemie 21
- HI
- dějiny 0
- EC
- ekonomika 0
- PK
- farmakokinetika 1
- PD
- farmakologie 2
- PH
- fyziologie 16
- GE
- genetika 158
- IM
- imunologie 20
- IP
- izolace a purifikace 10
- CL
- klasifikace 2
- BL
- krev 22
- ME
- metabolismus 146
- UR
- moč 3
- CF
- mozkomíšní mok 0
- DF
- nedostatek 1
- ST
- normy 0
- PO
- otrava 0
- AE
- škodlivé účinky 1
- TU
- terapeutické užití 6
- TO
- toxicita 0
- DE
- účinky léků 3
- RE
- účinky záření 0
- UL
- ultrastruktura 1
- SD
- zásobování a distribuce 0