Huntingtin Protein [protein huntingtin]
- Terms
-
protein Huntingtonovy choroby
protein IT15
-
Huntington Disease Protein
IT15 Protein
A protein that is highly expressed in the nervous system as well as other tissues; its size and structure vary due to polymorphisms. Expanded CAG TRINUCLEOTIDE REPEATS have been identified in the Huntingtin (HD) Gene of patients with HUNTINGTON DISEASE and are associated with abnormal PROTEIN AGGREGATES. Huntingtin interacts with proteins involved in a variety of gene expression and cellular processes; it is also essential for embryonic development.
- DUI
- D000071058 MeSH Browser
- CUI
- M000612972
- Previous indexing
- Nerve Tissue Proteins (2012-2016); Nuclear Proteins (1994-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects 3
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- DE
- drug effects 2
- EC
- economics
- GE
- genetics 22
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification 2
- ME
- metabolism 13
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
HTT protein, human Chemical MeSH Browser
Htt protein, Drosophila Chemical MeSH Browser
Htt protein, mouse Chemical MeSH Browser
Htt protein, rat Chemical MeSH Browser