Immune Checkpoint Proteins [proteiny kontrolních bodů imunitní reakce]

topical
7
Terms

proteiny imunitních kontrolních bodů

 

Immune Checkpoint Molecule
Immune Checkpoint Molecules
Immune Checkpoint Protein
Inhibitory Checkpoint Molecule
Inhibitory Checkpoint Molecules
Stimulatory Checkpoint Molecule
Stimulatory Checkpoint Molecules

Persistent link   https://www.medvik.cz/link/D000082102
Definition

Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules.

DUI
D000082102 MeSH Browser
CUI
M000675777
History note
2021
Public note
2021

Combination

antagonists & inhibitors
Immune Checkpoint Inhibitors

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 2
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 2
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 579
D12.776.034 Albumins 366
D12.776.037 Algal Proteins 18
D12.776.045 Amphibian Proteins 2
D12.776.049 Amyloid 166
D12.776.053 Antifreeze Proteins 4
D12.776.066 Antiviral Restriction Factors
D12.776.070 Apoproteins 31
D12.776.083 Aprotinin 53
D12.776.090 Archaeal Proteins 12
D12.776.091 Armadillo Domain Proteins 2
D12.776.093 Arthropod Proteins 43
D12.776.094 Autophagy-Related Proteins 7
D12.776.095 Avian Proteins 33
D12.776.097 Bacterial Proteins 1 024
D12.776.124 Blood Proteins 909
D12.776.157 Carrier Proteins 546
D12.776.167 Cell Cycle Proteins 330
D12.776.178 Cerebrospinal Fluid Proteins 128
D12.776.200 Colipases
D12.776.210 Contractile Proteins 27
D12.776.212 CRISPR-Associated Proteins 3
D12.776.215 Cystatins 83
D12.776.217 Cystine-Knot Miniproteins
D12.776.220 Cytoskeletal Proteins 101
D12.776.231 Dental Enamel Proteins 30
D12.776.256 Dietary Proteins 363
D12.776.260 DNA-Binding Proteins 561
D12.776.290 Egg Proteins 22
D12.776.298 Epididymal Secretory Proteins 8
D12.776.306 Eye Proteins 53
D12.776.313 Fanconi Anemia Complementation Group Proteins 6
D12.776.320 Fetal Proteins 123
D12.776.325 Fish Proteins 50
D12.776.331 Flavoproteins 24
D12.776.354 Fungal Proteins 272
D12.776.377 Globulins 68
D12.776.395 Glycoproteins 638
D12.776.407 Golgi Matrix Proteins
D12.776.419 Helminth Proteins 48
D12.776.422 Hemeproteins 16
D12.776.441 Huntingtin Protein 28
D12.776.460 Immediate-Early Proteins 8
D12.776.463 Immobilized Proteins 14
D12.776.465 Immune Checkpoint Proteins 7
D12.776.465.500 B7-2 Antigen 14
D12.776.465.625 B7-H1 Antigen 248
D12.776.465.750 CD40 Antigens 18
D12.776.465.782 CTLA-4 Antigen 192
D12.776.465.798 Hepatitis A Virus Cellular Receptor 2 7
D12.776.465.806 Lymphocyte Activation Gene 3 Protein 1
D12.776.465.813 OX40 Ligand 1
D12.776.465.829 Programmed Cell Death 1 Ligand 2 Protein 15
D12.776.465.844 Programmed Cell Death 1 Receptor 293
D12.776.465.875 Receptors, OX40 3
D12.776.467 Intercellular Signaling Peptides and Proteins 156
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.481 Intrinsically Disordered Proteins 24
D12.776.486 Iodoproteins 5
D12.776.494 Iron-Regulatory Proteins 7
D12.776.503 Lectins 295
D12.776.512 LIM Domain Proteins 10
D12.776.521 Lipoproteins 1 079
D12.776.526 LDL-Receptor Related Proteins 7
D12.776.529 Leucine-Rich Repeat Proteins
D12.776.532 Luminescent Proteins 44
D12.776.543 Membrane Proteins 850
D12.776.556 Metalloproteins 30
D12.776.575 Mitochondrial Proteins 209
D12.776.580 Molecular Chaperones 81
D12.776.602 Mutant Proteins 62
D12.776.624 Neoplasm Proteins 413
D12.776.631 Nerve Tissue Proteins 264
D12.776.660 Nuclear Proteins 455
D12.776.664 Nucleoproteins 91
D12.776.691 Oxidative Phosphorylation Coupling Factors 3
D12.776.705 Parkinson Disease Associated Proteins
D12.776.719 Peptones 21
D12.776.744 Phosphoproteins 189
D12.776.752 Photoreceptors, Microbial
D12.776.765 Plant Proteins 414
D12.776.775 Polyproteins 4
D12.776.780 Pregnancy Proteins 28
D12.776.785 Prions 152
D12.776.791 Protein Corona 11
D12.776.794 Protein Degradation End Products 1
D12.776.796 Protein Hydrolysates 50
D12.776.800 Protein Isoforms 259
D12.776.811 Protein Precursors 132
D12.776.813 Protein Subunits 107
D12.776.815 Proteinase Inhibitory Proteins, Secretory 5
D12.776.816 Proteolipids 13
D12.776.817 Proteome 357
D12.776.820 Protozoan Proteins 204
D12.776.823 Pulmonary Surfactant-Associated Proteins 7
D12.776.826 Receptors, Cytoplasmic and Nuclear 115
D12.776.827 Receptors, Drug 173
D12.776.828 Recombinant Proteins 888
D12.776.831 Reptilian Proteins 2
D12.776.835 Ribosomal Proteins 69
D12.776.850 Salivary Proteins and Peptides 52
D12.776.860 Scleroproteins 5
D12.776.861 Secretoglobins
D12.776.863 Selenium-Binding Proteins 3
D12.776.864 Selenoproteins 12
D12.776.869 Seminal Proteins 1
D12.776.872 Serpins 41
D12.776.884 Silver Proteins 9
D12.776.915 Thioredoxins 24
D12.776.922 Thymosin 8
D12.776.930 Transcription Factors 733
D12.776.934 Tripartite Motif Proteins 2
D12.776.938 Ubiquitinated Proteins 3
D12.776.947 Ubiquitins 20
D12.776.964 Viral Proteins 376
D23 Biological Factors 143
D23.050 Antigens 1 131
D23.063 Antioxidants 2 531
D23.101 Biomarkers 5 848
D23.113 Blood Coagulation Factor Inhibitors 112
D23.119 Blood Coagulation Factors 332
D23.125 Chemotactic Factors 14
D23.297 Host-Derived Cellular Factors 1
D23.383 Immune Checkpoint Proteins 7
D23.469 Inflammation Mediators 325
D23.529 Intercellular Signaling Peptides and Proteins 156
D23.585 Pathogen-Associated Molecular Pattern Molecules 16
D23.641 Pheromones 69
D23.704 Phytochemicals 70
D23.767 Pigments, Biological 74
D23.946 Toxins, Biological 262

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