B7-2 Antigen [antigeny CD86]
- Terms
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antigen B7-2
antigen CD86
kostimulační molekula B7-2
kostimulační molekula B70
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Antigen, B7-2
Antigens, CD86
B7-2 Costimulatory Molecule
B70 Costimulatory Molecule
CD86 Antigen
CD86 Antigens
Early T Cell Costimulatory Molecule 1
A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
- DUI
- D051940 MeSH Browser
- CUI
- M0223248
- History note
- 2018 (1993)
- Public note
- 2018; see ANTIGENS, CD86 2006-2017; B7-2 ANTIGEN was indexed under MEMBRANE GLYCOPROTEINS and ANTIGENS, CD 1996-2005; and under B-CELL ACTIVATION ANTIGEN 1993-1995
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis 2
- AI
- antagonists & inhibitors
- BI
- biosynthesis 6
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology 3
- IP
- isolation & purification
- ME
- metabolism 3
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
CD86 protein, human Chemical MeSH Browser
Cd86 protein, mouse Chemical MeSH Browser
Cd86 protein, rat Chemical MeSH Browser