Huntingtin Protein [protein huntingtin]
topical
28
- Terms
-
protein Huntingtonovy choroby
protein IT15
-
Huntington Disease Protein
IT15 Protein
Persistent link
https://www.medvik.cz/link/D000071058
Definition
A protein that is highly expressed in the nervous system as well as other tissues; its size and structure vary due to polymorphisms. Expanded CAG TRINUCLEOTIDE REPEATS have been identified in the Huntingtin (HD) Gene of patients with HUNTINGTON DISEASE and are associated with abnormal PROTEIN AGGREGATES. Huntingtin interacts with proteins involved in a variety of gene expression and cellular processes; it is also essential for embryonic development.
- DUI
- D000071058 MeSH Browser
- CUI
- M000612972
- Previous indexing
- Nerve Tissue Proteins (2012-2016); Nuclear Proteins (1994-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 3
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 1
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 2
- EC
- economics 0
- GE
- genetics 22
- HI
- history 0
- IM
- immunology 1
- IP
- isolation & purification 2
- ME
- metabolism 13
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 1
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.776.066
Antiviral Restriction Factors
D12.776.200
Colipases
D12.776.217
Cystine-Knot Miniproteins
D12.776.407
Golgi Matrix Proteins
D12.776.529
Leucine-Rich Repeat Proteins
D12.776.705
Parkinson Disease Associated Proteins
D12.776.752
Photoreceptors, Microbial
D12.776.861
Secretoglobins