MDS1 and EVI1 Complex Locus Protein [protein MDS1 and EVI1 complex locus]

topical
2
Terms

protein MECOM
protein s motivem zinkového prstu Evi1

 

Ecotropic Virus Integration Site 1 Protein Homolog
MECOM Protein
Myelodysplasia Syndrome-Associated Protein 1
Zinc Finger Protein Evi1

Persistent link   https://www.medvik.cz/link/D000074008
Definition

A DNA binding protein, transcriptional regulator, and proto-oncogene protein that contains 10 CYS2-HIS2 ZINC FINGERS. It functions as a positive or negative regulator of expression for target genes involved in organism development.

DUI
D000074008 MeSH Browser
CUI
M000625171
Previous indexing
DNA-Binding Proteins (1990-2017); Proto-Oncogenes (1990-2017); Transcription Factors (1990-2017)
History note
2018
Public note
2018

Allowable subheadings

AD
administration & dosage 0
AE
adverse effects 0
AG
agonists 0
AN
analysis 0
AI
antagonists & inhibitors 0
BI
biosynthesis 0
BL
blood 0
CF
cerebrospinal fluid 0
CS
chemical synthesis 0
CH
chemistry 0
CL
classification 0
DF
deficiency 0
DE
drug effects 0
EC
economics 0
GE
genetics 0
HI
history 0
IM
immunology 0
IP
isolation & purification 0
ME
metabolism 1
PK
pharmacokinetics 0
PD
pharmacology 0
PH
physiology 0
PO
poisoning 0
RE
radiation effects 0
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 0
TO
toxicity 0
UL
ultrastructure 0
UR
urine 0

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 575
D12.776.260 DNA-Binding Proteins 553
D12.776.260.060 Adenovirus E2 Proteins 1
D12.776.260.103 Basic Helix-Loop-Helix Transcription Factors 61
D12.776.260.108 Basic-Leucine Zipper Transcription Factors 18
D12.776.260.114 Butyrate Response Factor 1
D12.776.260.120 CCCTC-Binding Factor 2
D12.776.260.123 Centromere Protein A 2
D12.776.260.125 Centromere Protein B
D12.776.260.158 Early Growth Response Transcription Factors 1
D12.776.260.197 Elongin
D12.776.260.235 Erythroid-Specific DNA-Binding Factors 1
D12.776.260.246 Factor For Inversion Stimulation Protein
D12.776.260.254 G-Box Binding Factors
D12.776.260.257 GATA Transcription Factors 2
D12.776.260.260 Heat Shock Transcription Factors 1
D12.776.260.262 Hepatocyte Nuclear Factors 5
D12.776.260.268 Heterogeneous-Nuclear Ribonucleoprotein K
D12.776.260.312 HMGA Proteins 1
D12.776.260.356 HMGB Proteins 4
D12.776.260.400 Homeodomain Proteins 122
D12.776.260.420 I-kappa B Proteins 5
D12.776.260.457 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.260.495 Integration Host Factors
D12.776.260.504 Interferon Regulatory Factors 11
D12.776.260.513 Interferon-Stimulated Gene Factor 3
D12.776.260.522 Kruppel-Like Transcription Factors 26
D12.776.260.525 Ku Autoantigen 5
D12.776.260.527 Leucine-Responsive Regulatory Protein
D12.776.260.529 LIM-Homeodomain Proteins 5
D12.776.260.531 Liver X Receptors 5
D12.776.260.532 Matrix Attachment Region Binding Proteins 9
D12.776.260.534 MDS1 and EVI1 Complex Locus Protein 2
D12.776.260.536 Methyl-CpG-Binding Protein 2 12
D12.776.260.538 Minichromosome Maintenance 1 Protein 1
D12.776.260.539 MRE11 Homologue Protein 6
D12.776.260.540 MutL Proteins
D12.776.260.556 MutS Proteins
D12.776.260.560 Myeloid-Lymphoid Leukemia Protein 39
D12.776.260.600 NF-kappa B 209
D12.776.260.605 NFI Transcription Factors 6
D12.776.260.615 Nuclear Respiratory Factors
D12.776.260.623 Nucleobindins 2
D12.776.260.630 Oncogene Protein p55(v-myc) 1
D12.776.260.640 Origin Recognition Complex 1
D12.776.260.643 Orphan Nuclear Receptors 2
D12.776.260.645 Paired Box Transcription Factors 21
D12.776.260.650 Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 4
D12.776.260.655 POU Domain Factors 4
D12.776.260.660 Proto-Oncogene Proteins c-bcl-6 3
D12.776.260.665 Proto-Oncogene Proteins c-ets 19
D12.776.260.675 Proto-Oncogene Proteins c-myb 30
D12.776.260.682 Proto-Oncogene Proteins c-rel 2
D12.776.260.690 Proto-Oncogene Proteins c-sis 3
D12.776.260.693 PTB-Associated Splicing Factor
D12.776.260.695 Rad51 Recombinase 42
D12.776.260.696 Rad52 DNA Repair and Recombination Protein 9
D12.776.260.700 Replication Protein A 12
D12.776.260.702 Replication Protein C 3
D12.776.260.703 Repressor Proteins 189
D12.776.260.704 Retinoblastoma Protein 52
D12.776.260.713 Smad Proteins 14
D12.776.260.716 SMARCB1 Protein 15
D12.776.260.719 SOX Transcription Factors 1
D12.776.260.725 T-Box Domain Proteins 14
D12.776.260.730 TCF Transcription Factors 3
D12.776.260.733 TEA Domain Transcription Factors 3
D12.776.260.735 Telomere-Binding Proteins 24
D12.776.260.750 Toll-Like Receptor 9 15
D12.776.260.755 Trans-Activators 110
D12.776.260.760 Transcription Factor AP-2 1
D12.776.260.768 Transcription Factor MTF-1
D12.776.260.775 Transcription Factors, General 1
D12.776.260.790 Tristetraprolin 2
D12.776.260.805 Tumor Suppressor p53-Binding Protein 1 16
D12.776.260.820 Tumor Suppressor Protein p53 754
D12.776.260.885 Tumor Protein p73 6
D12.776.260.950 Winged-Helix Transcription Factors
D12.776.260.963 X-ray Repair Cross Complementing Protein 1 9
D12.776.260.975 Xeroderma Pigmentosum Group A Protein 2
D12.776.624 Neoplasm Proteins 411
D12.776.624.664 Oncogene Proteins 124
D12.776.624.664.700 Proto-Oncogene Proteins 263
D12.776.624.664.700.013 Axl Receptor Tyrosine Kinase
D12.776.624.664.700.025 Bcl-2-Like Protein 11 5
D12.776.624.664.700.037 c-Mer Tyrosine Kinase 2
D12.776.624.664.700.049 Chemokine CXCL1 7
D12.776.624.664.700.100 Cyclin D1 86
D12.776.624.664.700.110 Fibroblast Growth Factor 4 2
D12.776.624.664.700.112 Fibroblast Growth Factor 6
D12.776.624.664.700.114 fms-Like Tyrosine Kinase 3 49
D12.776.624.664.700.117 Janus Kinase 2 78
D12.776.624.664.700.119 KRIT1 Protein
D12.776.624.664.700.120 Kruppel-Like Factor 6 1
D12.776.624.664.700.123 Lipocalin-2 20
D12.776.624.664.700.128 Lymphocyte Specific Protein Tyrosine Kinase p56(lck) 10
D12.776.624.664.700.129 MDS1 and EVI1 Complex Locus Protein 2
D12.776.624.664.700.130 MutS Homolog 2 Protein 17
D12.776.624.664.700.148 Myeloid-Lymphoid Leukemia Protein 39
D12.776.624.664.700.158 N-Myc Proto-Oncogene Protein 8
D12.776.624.664.700.163 Pre-B-Cell Leukemia Transcription Factor 1 2
D12.776.624.664.700.165 B-Cell Lymphoma 3 Protein
D12.776.624.664.700.166 Proto-Oncogene Mas 2
D12.776.624.664.700.167 Proto-Oncogene Proteins c-abl 7
D12.776.624.664.700.168 Proto-Oncogene Proteins c-akt 113
D12.776.624.664.700.169 Proto-Oncogene Proteins c-bcl-2 147
D12.776.624.664.700.170 Proto-Oncogene Proteins c-bcl-6 3
D12.776.624.664.700.171 Proto-Oncogene Proteins c-bcr 19
D12.776.624.664.700.172 Proto-Oncogene Proteins c-cbl 5
D12.776.624.664.700.174 Proto-Oncogene Proteins c-crk 1
D12.776.624.664.700.175 Proto-Oncogene Proteins c-ets 19
D12.776.624.664.700.177 Proto-Oncogene Proteins c-fes
D12.776.624.664.700.179 Proto-Oncogene Proteins c-fos 61
D12.776.624.664.700.180 Proto-Oncogene Proteins c-fyn 4
D12.776.624.664.700.181 Proto-Oncogene Proteins c-hck 1
D12.776.624.664.700.182 Proto-Oncogene Proteins c-jun 17
D12.776.624.664.700.183 Proto-Oncogene Proteins c-kit 77
D12.776.624.664.700.184 Proto-Oncogene Proteins c-maf 1
D12.776.624.664.700.185 Proto-Oncogene Proteins c-mdm2 65
D12.776.624.664.700.186 Proto-Oncogene Proteins c-met 30
D12.776.624.664.700.187 Proto-Oncogene Proteins c-mos 2
D12.776.624.664.700.188 Proto-Oncogene Proteins c-myb 30
D12.776.624.664.700.189 Proto-Oncogene Proteins c-myc 66
D12.776.624.664.700.191 Proto-Oncogene Proteins c-pim-1 1
D12.776.624.664.700.192 Proto-Oncogene Proteins c-rel 2
D12.776.624.664.700.194 Proto-Oncogene Proteins c-ret 42
D12.776.624.664.700.195 Proto-Oncogene Proteins c-sis 3
D12.776.624.664.700.198 Proto-Oncogene Proteins c-vav 4
D12.776.624.664.700.199 Proto-Oncogene Proteins c-yes 1
D12.776.624.664.700.200 Proto-Oncogene Proteins p21(ras) 71
D12.776.624.664.700.202 Proto-Oncogene Proteins pp60(c-src) 7
D12.776.624.664.700.204 raf Kinases 70
D12.776.624.664.700.642 Receptor, ErbB-2 583
D12.776.624.664.700.790 Receptor, ErbB-3 9
D12.776.624.664.700.791 Receptor, ErbB-4
D12.776.624.664.700.792 Receptor, Fibroblast Growth Factor, Type 3 27
D12.776.624.664.700.800 Receptor, Macrophage Colony-Stimulating Factor 1
D12.776.624.664.700.815 Receptor, Notch4
D12.776.624.664.700.830 Receptors, Thyroid Hormone 40
D12.776.624.664.700.913 RNA-Binding Protein EWS 15
D12.776.624.664.700.915 RNA-Binding Protein FUS 6
D12.776.624.664.700.936 RUNX1 Translocation Partner 1 Protein
D12.776.624.664.700.957 Stathmin 4
D12.776.624.664.700.960 T-Cell Acute Lymphocytic Leukemia Protein 1
D12.776.624.664.700.962 Wnt-5a Protein 5
D12.776.624.664.700.967 Wnt1 Protein 4
D12.776.624.664.700.978 Wnt2 Protein
D12.776.624.664.700.989 Zinc Finger Protein GLI1 7
D12.776.930 Transcription Factors 722
D12.776.930.100 Adenovirus E1A Proteins 5
D12.776.930.110 Adenovirus E1B Proteins 3
D12.776.930.120 Antennapedia Homeodomain Protein 1
D12.776.930.123 AIRE Protein 2
D12.776.930.125 Basic Helix-Loop-Helix Transcription Factors 61
D12.776.930.127 Basic-Leucine Zipper Transcription Factors 18
D12.776.930.130 beta Catenin 97
D12.776.930.137 BRCA1 Protein 101
D12.776.930.146 CDX2 Transcription Factor 3
D12.776.930.155 Core Binding Factors 3
D12.776.930.160 COUP Transcription Factors
D12.776.930.165 Cyclic AMP Receptor Protein 2
D12.776.930.211 E2F Transcription Factors 16
D12.776.930.213 Early Growth Response Transcription Factors 1
D12.776.930.215 Elongin
D12.776.930.216 Erythroid-Specific DNA-Binding Factors 1
D12.776.930.312 Fushi Tarazu Transcription Factors
D12.776.930.313 G-Box Binding Factors
D12.776.930.314 GATA Transcription Factors 2
D12.776.930.315 Goosecoid Protein 2
D12.776.930.317 Heat Shock Transcription Factors 1
D12.776.930.318 Hepatocyte Nuclear Factors 5
D12.776.930.320 Homeobox Protein PITX2
D12.776.930.321 Homeobox Protein Nkx-2.2
D12.776.930.324 Homeobox Protein Nkx-2.5 1
D12.776.930.325 Host Cell Factor C1 2
D12.776.930.326 I-kappa B Proteins 5
D12.776.930.327 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.930.329 Inhibitor of Differentiation Proteins 2
D12.776.930.332 Interferon Regulatory Factors 11
D12.776.930.354 Interferon-Stimulated Gene Factor 3
D12.776.930.375 Kruppel-Like Transcription Factors 26
D12.776.930.386 Leucine-Responsive Regulatory Protein
D12.776.930.397 MADS Domain Proteins 3
D12.776.930.419 MDS1 and EVI1 Complex Locus Protein 2
D12.776.930.440 MSX1 Transcription Factor 8
D12.776.930.462 Myeloid Ecotropic Viral Integration Site 1 Protein 1
D12.776.930.483 Myeloid-Lymphoid Leukemia Protein 39
D12.776.930.542 Nanog Homeobox Protein 3
D12.776.930.600 NF-kappa B 209
D12.776.930.608 NFATC Transcription Factors 13
D12.776.930.612 NFI Transcription Factors 6
D12.776.930.616 Nuclear Factor 90 Proteins
D12.776.930.617 Nuclear Receptor Coactivators 6
D12.776.930.618 Nuclear Respiratory Factors
D12.776.930.640 Onecut Transcription Factors
D12.776.930.645 Orphan Nuclear Receptors 2
D12.776.930.650 Otx Transcription Factors 4
D12.776.930.680 p300-CBP Transcription Factors 5
D12.776.930.700 Paired Box Transcription Factors 21
D12.776.930.705 Peroxisome Proliferator-Activated Receptors 54
D12.776.930.710 POU Domain Factors 4
D12.776.930.712 Pre-B-Cell Leukemia Transcription Factor 1 2
D12.776.930.713 Promyelocytic Leukemia Protein 4
D12.776.930.714 B-Cell Lymphoma 3 Protein
D12.776.930.715 Proto-Oncogene Proteins c-bcl-6 3
D12.776.930.720 Proto-Oncogene Proteins c-ets 19
D12.776.930.725 Proto-Oncogene Proteins c-myb 30
D12.776.930.730 Proto-Oncogene Proteins c-rel 2
D12.776.930.760 Receptors, Aryl Hydrocarbon 133
D12.776.930.770 Receptors, Notch 20
D12.776.930.775 Receptors, Retinoic Acid 42
D12.776.930.778 Receptors, Steroid 143
D12.776.930.780 Repressor Proteins 189
D12.776.930.785 Rho Factor 12
D12.776.930.800 Sigma Factor 55
D12.776.930.806 Smad Proteins 14
D12.776.930.809 SMARCB1 Protein 15
D12.776.930.815 Snail Family Transcription Factors 4
D12.776.930.823 SOX Transcription Factors 1
D12.776.930.840 STAT Transcription Factors 23
D12.776.930.850 T-Box Domain Proteins 14
D12.776.930.875 TCF Transcription Factors 3
D12.776.930.882 TEA Domain Transcription Factors 3
D12.776.930.888 Thyroid Nuclear Factor 1
D12.776.930.900 Trans-Activators 110
D12.776.930.907 Transcription Factor AP-2 1
D12.776.930.908 Transcription Factor DP1 10
D12.776.930.919 Transcription Factor MTF-1
D12.776.930.930 Transcription Factors, General 1
D12.776.930.955 Transcriptional Elongation Factors 8
D12.776.930.960 Tristetraprolin 2
D12.776.930.969 Tumor Protein p73 6
D12.776.930.977 Winged-Helix Transcription Factors

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