CCCTC-Binding Factor [CCCTC-vazebný faktor]

topical
2
Terms

DNA-vazebný protein CTCF
protein CTCF

 

CTCF Protein
DNA-Binding Protein CTCF

Persistent link   https://www.medvik.cz/link/D000076246
Definition

A repressor protein with poly(ADP)-ribose binding activity that binds CHROMATIN and DNA; its structure consisting of 11 CYS2-HIS2 ZINC FINGERS allows it to recognize many different DNA target sites. It functions as a repressor by binding to INSULATOR ELEMENTS and preventing interaction between promoters and nearby enhancers and silencers. It plays a critical role in EPIGENETIC PROCESSES, including GENOMIC IMPRINTING.

DUI
D000076246 MeSH Browser
CUI
M0284805
History note
2018 (1998)
Public note
2018; CCCTC-BINDING FACTOR was indexed under REPRESSOR PROTEINS 2010-2017, under DNA-BINDING PROTEINS 1998-2009; and under TRANSCRIPTION FACTORS 1998-2004

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 2
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.157 Carrier Proteins 546
D12.776.157.687 Poly-ADP-Ribose Binding Proteins 5
D12.776.157.687.063 Apoptosis Inducing Factor 10
D12.776.157.687.125 Ataxia Telangiectasia Mutated Proteins 89
D12.776.157.687.157 CCCTC-Binding Factor 2
D12.776.157.687.173 Centromere Protein A 2
D12.776.157.687.188 Centromere Protein B
D12.776.157.687.250 Cyclin-Dependent Kinase Inhibitor p21 74
D12.776.157.687.313 DNA (Cytosine-5-)-Methyltransferase 1 7
D12.776.157.687.375 DNA Topoisomerases, Type I 24
D12.776.157.687.438 DNA-Activated Protein Kinase 14
D12.776.157.687.450 Heat Shock Transcription Factors 1
D12.776.157.687.462 Heterogeneous Nuclear Ribonucleoprotein A1
D12.776.157.687.485 Histones 368
D12.776.157.687.493 Ku Autoantigen 5
D12.776.157.687.495 MRE11 Homologue Protein 6
D12.776.157.687.496 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.157.687.497 NF-kappa B p52 Subunit 2
D12.776.157.687.499 Nicotinamide-Nucleotide Adenylyltransferase 3
D12.776.157.687.575 Nitric Oxide Synthase Type II 75
D12.776.157.687.613 Telomerase 189
D12.776.157.687.650 Tumor Suppressor Protein p53 755
D12.776.157.687.750 Werner Syndrome Helicase 2
D12.776.157.687.813 X-ray Repair Cross Complementing Protein 1 9
D12.776.157.687.875 Xeroderma Pigmentosum Group A Protein 2
D12.776.260 DNA-Binding Proteins 556
D12.776.260.060 Adenovirus E2 Proteins 1
D12.776.260.103 Basic Helix-Loop-Helix Transcription Factors 61
D12.776.260.108 Basic-Leucine Zipper Transcription Factors 18
D12.776.260.114 Butyrate Response Factor 1
D12.776.260.120 CCCTC-Binding Factor 2
D12.776.260.123 Centromere Protein A 2
D12.776.260.125 Centromere Protein B
D12.776.260.158 Early Growth Response Transcription Factors 1
D12.776.260.197 Elongin
D12.776.260.235 Erythroid-Specific DNA-Binding Factors 1
D12.776.260.246 Factor For Inversion Stimulation Protein
D12.776.260.254 G-Box Binding Factors
D12.776.260.257 GATA Transcription Factors 2
D12.776.260.260 Heat Shock Transcription Factors 1
D12.776.260.262 Hepatocyte Nuclear Factors 5
D12.776.260.268 Heterogeneous-Nuclear Ribonucleoprotein K
D12.776.260.312 HMGA Proteins 1
D12.776.260.356 HMGB Proteins 4
D12.776.260.400 Homeodomain Proteins 122
D12.776.260.420 I-kappa B Proteins 5
D12.776.260.457 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.260.495 Integration Host Factors
D12.776.260.504 Interferon Regulatory Factors 11
D12.776.260.513 Interferon-Stimulated Gene Factor 3
D12.776.260.522 Kruppel-Like Transcription Factors 26
D12.776.260.525 Ku Autoantigen 5
D12.776.260.527 Leucine-Responsive Regulatory Protein
D12.776.260.529 LIM-Homeodomain Proteins 5
D12.776.260.531 Liver X Receptors 5
D12.776.260.532 Matrix Attachment Region Binding Proteins 9
D12.776.260.534 MDS1 and EVI1 Complex Locus Protein 2
D12.776.260.536 Methyl-CpG-Binding Protein 2 12
D12.776.260.538 Minichromosome Maintenance 1 Protein 1
D12.776.260.539 MRE11 Homologue Protein 6
D12.776.260.540 MutL Proteins
D12.776.260.556 MutS Proteins
D12.776.260.560 Myeloid-Lymphoid Leukemia Protein 39
D12.776.260.600 NF-kappa B 218
D12.776.260.605 NFI Transcription Factors 6
D12.776.260.615 Nuclear Respiratory Factors
D12.776.260.623 Nucleobindins 3
D12.776.260.630 Oncogene Protein p55(v-myc) 1
D12.776.260.640 Origin Recognition Complex 1
D12.776.260.643 Orphan Nuclear Receptors 2
D12.776.260.645 Paired Box Transcription Factors 21
D12.776.260.650 Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 4
D12.776.260.655 POU Domain Factors 4
D12.776.260.660 Proto-Oncogene Proteins c-bcl-6 3
D12.776.260.665 Proto-Oncogene Proteins c-ets 19
D12.776.260.675 Proto-Oncogene Proteins c-myb 30
D12.776.260.682 Proto-Oncogene Proteins c-rel 2
D12.776.260.690 Proto-Oncogene Proteins c-sis 3
D12.776.260.693 PTB-Associated Splicing Factor
D12.776.260.695 Rad51 Recombinase 42
D12.776.260.696 Rad52 DNA Repair and Recombination Protein 9
D12.776.260.700 Replication Protein A 12
D12.776.260.702 Replication Protein C 3
D12.776.260.703 Repressor Proteins 189
D12.776.260.704 Retinoblastoma Protein 52
D12.776.260.713 Smad Proteins 14
D12.776.260.716 SMARCB1 Protein 15
D12.776.260.719 SOX Transcription Factors 1
D12.776.260.725 T-Box Domain Proteins 14
D12.776.260.730 TCF Transcription Factors 3
D12.776.260.733 TEA Domain Transcription Factors 3
D12.776.260.735 Telomere-Binding Proteins 24
D12.776.260.750 Toll-Like Receptor 9 16
D12.776.260.755 Trans-Activators 110
D12.776.260.760 Transcription Factor AP-2 1
D12.776.260.768 Transcription Factor MTF-1
D12.776.260.775 Transcription Factors, General 1
D12.776.260.790 Tristetraprolin 2
D12.776.260.805 Tumor Suppressor p53-Binding Protein 1 16
D12.776.260.820 Tumor Suppressor Protein p53 755
D12.776.260.885 Tumor Protein p73 6
D12.776.260.950 Winged-Helix Transcription Factors
D12.776.260.963 X-ray Repair Cross Complementing Protein 1 9
D12.776.260.975 Xeroderma Pigmentosum Group A Protein 2
D12.776.660 Nuclear Proteins 452
D12.776.660.235 Chromosomal Proteins, Non-Histone 93
D12.776.660.235.025 Bromodomain Containing Proteins 3
D12.776.660.235.050 CCCTC-Binding Factor 2
D12.776.660.235.100 Centromere Protein A 2
D12.776.660.235.199 Centromere Protein B
D12.776.660.235.300 Chromobox Protein Homolog 5
D12.776.660.235.350 Cohesins
D12.776.660.235.400 High Mobility Group Proteins 20
D12.776.660.235.500 Minichromosome Maintenance Proteins 4
D12.776.660.235.550 Methyl-CpG-Binding Protein 2 12
D12.776.660.235.600 Polycomb-Group Proteins 7
D12.776.660.235.650 SMARCB1 Protein 15
D12.776.660.235.675 Structural Maintenance of Chromosome Protein 1
D12.776.660.235.700 Telomere-Binding Proteins 24
D12.776.660.235.850 Tumor Suppressor p53-Binding Protein 1 16
D12.776.660.720 Poly-ADP-Ribose Binding Proteins 5
D12.776.660.720.063 Apoptosis Inducing Factor 10
D12.776.660.720.125 Ataxia Telangiectasia Mutated Proteins 89
D12.776.660.720.157 CCCTC-Binding Factor 2
D12.776.660.720.173 Centromere Protein A 2
D12.776.660.720.188 Centromere Protein B
D12.776.660.720.250 Cyclin-Dependent Kinase Inhibitor p21 74
D12.776.660.720.313 DNA (Cytosine-5-)-Methyltransferase 1 7
D12.776.660.720.375 DNA Topoisomerases, Type I 24
D12.776.660.720.438 DNA-Activated Protein Kinase 14
D12.776.660.720.462 Heat Shock Transcription Factors 1
D12.776.660.720.485 Histones 368
D12.776.660.720.493 Ku Autoantigen 5
D12.776.660.720.495 MRE11 Homologue Protein 6
D12.776.660.720.496 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.660.720.497 NF-kappa B p52 Subunit 2
D12.776.660.720.499 Nicotinamide-Nucleotide Adenylyltransferase 3
D12.776.660.720.575 Nitric Oxide Synthase Type II 75
D12.776.660.720.613 Telomerase 189
D12.776.660.720.650 Tumor Suppressor Protein p53 755
D12.776.660.720.750 Werner Syndrome Helicase 2
D12.776.660.720.813 X-ray Repair Cross Complementing Protein 1 9
D12.776.660.720.875 Xeroderma Pigmentosum Group A Protein 2
D12.776.664 Nucleoproteins 91
D12.776.664.235 Chromosomal Proteins, Non-Histone 93
D12.776.664.235.025 Bromodomain Containing Proteins 3
D12.776.664.235.050 CCCTC-Binding Factor 2
D12.776.664.235.100 Centromere Protein A 2
D12.776.664.235.199 Centromere Protein B
D12.776.664.235.300 Chromobox Protein Homolog 5
D12.776.664.235.350 Cohesins
D12.776.664.235.400 High Mobility Group Proteins 20
D12.776.664.235.700 Methyl-CpG-Binding Protein 2 12
D12.776.664.235.750 Minichromosome Maintenance Proteins 4
D12.776.664.235.800 Polycomb-Group Proteins 7
D12.776.664.235.900 SMARCB1 Protein 15
D12.776.664.235.925 Structural Maintenance of Chromosome Protein 1
D12.776.664.235.950 Tumor Suppressor p53-Binding Protein 1 16
D12.776.930 Transcription Factors 727
D12.776.930.780 Repressor Proteins 189
D12.776.930.780.500 AraC Transcription Factor
D12.776.930.780.563 CCCTC-Binding Factor 2
D12.776.930.780.625 Co-Repressor Proteins 6
D12.776.930.780.750 COUP Transcription Factor II 1
D12.776.930.780.766 ETS Translocation Variant 6 Protein 1
D12.776.930.780.781 Lac Repressors 2
D12.776.930.780.890 Polycomb-Group Proteins 7
D12.776.930.780.904 Positive Regulatory Domain I-Binding Factor 1 2
D12.776.930.780.911 Tripartite Motif-Containing Protein 28
D12.776.930.780.918 Zinc Finger E-box Binding Homeobox 2 3
D12.776.930.780.945 Zinc Finger E-box-Binding Homeobox 1 6
D12.776.930.780.972 Zinc Finger Protein Gli3

CTCF protein, Drosophila Chemical MeSH Browser

CTCF protein, human Chemical MeSH Browser

Ctcf protein, mouse Chemical MeSH Browser

Ctcf protein, rat Chemical MeSH Browser

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