Positive Regulatory Domain I-Binding Factor 1 [protein PRDI-BF1]
- Terms
-
protein BLIMP1
protein PRDM1
-
B Lymphocyte-Induced Maturation Protein 1
BLIMP1 Protein
PRDI-BF1 Protein
PRDM1 Protein
A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.
- DUI
- D000074462 MeSH Browser
- CUI
- M000626717
- Previous indexing
- Repressor Proteins (1994-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
PRDM1 protein, human Chemical MeSH Browser
Prdm1 protein, mouse Chemical MeSH Browser
prdm1a protein, zebrafish Chemical MeSH Browser