Positive Regulatory Domain I-Binding Factor 1 [protein PRDI-BF1]
topical
2
- Terms
-
protein BLIMP1
protein PRDM1
-
B Lymphocyte-Induced Maturation Protein 1
BLIMP1 Protein
PRDI-BF1 Protein
PRDM1 Protein
Persistent link
https://www.medvik.cz/link/D000074462
Definition
A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.
- DUI
- D000074462 MeSH Browser
- CUI
- M000626717
- Previous indexing
- Repressor Proteins (1994-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 1
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 1
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.913.555
One-Carbon Group Transferases
D08.811.913.555.500.800.800
Protein O-Methyltransferase
D12.776.260.703.099
AraC Transcription Factor
D12.776.260.703.675
Tripartite Motif-Containing Protein 28
D12.776.260.703.900
Zinc Finger Protein Gli3
D12.776.930.780.500
AraC Transcription Factor
D12.776.930.780.911
Tripartite Motif-Containing Protein 28
D12.776.930.780.972
Zinc Finger Protein Gli3