• Je něco špatně v tomto záznamu ?

Predictive Factors for Survival in Children Receiving Liver Transplants for Wilson's Disease: A Cohort Study Using European Liver Transplant Registry Data

ED. Pfister, A. Karch, R. Adam, WG. Polak, V. Karam, D. Mirza, J. O'Grady, J. Klempnauer, R. Reding, P. Kalicinski, A. Coker, P. Trunecka, I. Astarcioglu, E. Jacquemin, J. Pratschke, A. Paul, I. Popescu, S. Schneeberger, O. Boillot, L. Fischer,...

. 2018 ; 24 (9) : 1186-1198. [pub] -

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, multicentrická studie

Perzistentní odkaz   https://www.medvik.cz/link/bmc19028316

Liver transplantation (LT) is a rescue therapy for life-threatening complications of Wilson's disease (WD). However, data on the outcome of WD patients after LT are scarce. The aim of our study was to analyze a large pediatric WD cohort with the aim of investigating the longterm outcome of pediatric WD patients after LT and to identify predictive factors for patient and transplant survival. This is a retrospective cohort study using data of all children (<18 years) transplanted for WD enrolled in the European Liver Transplant Registry from January 1968 until December 2013. In total, 338 patients (57.6% female) transplanted at 80 different European centers (1-26 patients per center) were included in this study. The median age at transplantation was 14.0 years (interquartile range [IQR], 11.2-16.1 years); patients were followed up for a median of 5.4 years (IQR, 1.0-10.9 years) after LT. Overall patient survival rates were high with 87% (1-year survival), 84% (5-year survival), and 81% (10-year survival); survival rates increased considerably with the calendar year (P < 0.001). Early age at LT, living donation, and histidine tryptophan ketoglutarate preservation liquid were identified as risk factors for poor patient survival in the multivariate analysis. LT is an excellent treatment option for pediatric patients with WD and associated end-stage liver disease. Longterm outcome in these patients is similar to other pediatric causes for LT. Overall patient and graft survival rates improved considerably over the last decades. To improve future research in the field, the vast variability of allocation strategies should be harmonized and a generally accepted definition or discrimination of acute versus chronic WD needs to be found.

AP HP Hôpital Paul Brousse Université Paris Sud Center Hépato Biliaire INSERM U 935 Villejuif France

Cliniques Universitaires Saint Luc Brussels Belgium

Department of Gastroenterology Bozyaka Training and Research Hospital Izmir Turkey

Department of General and Transplant Surgery University Hospital Essen Essen Germany

Department of General Surgery and Liver Transplantation Fundeni Clinical Institute Bucharest Romania

Department of Hepatobiliary Surgery and Visceral Transplantation University Medical Center Hamburg Eppendorf Hamburg Germany

Department of Hepatology and Liver Transplant Unit AP HP Henri Mondor Hospital Paris Est University Créteil France

Department of Pediatric and Transplant Surgery Children's Memorial Health Institute Warsaw Poland

Department of Surgery Charite Berlin Germany

Department of Visceral Transplant and Thoracic Surgery Center of Operative Medicine Innsbruck Medical University Innsbruck Austria

Division of Pediatric Gastroenterology and Hepatology Departments of Pediatric Kidney Liver and Metabolic Diseases Hannover Germany

Erasmus University Rotterdam Rotterdam the Netherlands

European Liver Transplant Registry AP HP Hôpital Paul Brousse Université Paris Sud Center Hépato Biliaire INSERM U 935 Villejuif France

General Visceral and Transplantation Surgery Hannover Medical School Hannover Germany

HPB Surgery and Liver Transplantation Unit Department of General Surgery School of Medicine Dokuz Eylul University Inciralti İzmir Turkey

Institute of Liver Studies King's College Hospital London United Kingdom

Liver Transplant Unit Edouard Herriot Hospital Lyon France

Liver Unit Elizabeth Hospital Birmingham University Hospitals Birmingham National Health Service Foundation Trust Birmingham United Kingdom

Research Group Epidemiological and Statistical Methods Helmholtz Center for Infection Research Braunschweig Germany German Center for Infection Research Hannover Braunschweig Germany

Transplant Center Institute for Clinical and Experimental Medicine Prague Czech Republic

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc19028316
003      
CZ-PrNML
005      
20230808090925.0
007      
ta
008      
190813s2018 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1002/lt.25308 $2 doi
035    __
$a (PubMed)30021057
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Pfister, Eva-Doreen $u Division of Pediatric Gastroenterology and Hepatology, Departments of Pediatric Kidney, Liver, and Metabolic Diseases, Hannover, Germany.
245    10
$a Predictive Factors for Survival in Children Receiving Liver Transplants for Wilson's Disease: A Cohort Study Using European Liver Transplant Registry Data / $c ED. Pfister, A. Karch, R. Adam, WG. Polak, V. Karam, D. Mirza, J. O'Grady, J. Klempnauer, R. Reding, P. Kalicinski, A. Coker, P. Trunecka, I. Astarcioglu, E. Jacquemin, J. Pratschke, A. Paul, I. Popescu, S. Schneeberger, O. Boillot, L. Fischer, RT. Mikolajczyk, U. Baumann, C. Duvoux, for all European Liver Transplant Registry contributing centers and the European Liver Intestine Transplant Association,
520    9_
$a Liver transplantation (LT) is a rescue therapy for life-threatening complications of Wilson's disease (WD). However, data on the outcome of WD patients after LT are scarce. The aim of our study was to analyze a large pediatric WD cohort with the aim of investigating the longterm outcome of pediatric WD patients after LT and to identify predictive factors for patient and transplant survival. This is a retrospective cohort study using data of all children (<18 years) transplanted for WD enrolled in the European Liver Transplant Registry from January 1968 until December 2013. In total, 338 patients (57.6% female) transplanted at 80 different European centers (1-26 patients per center) were included in this study. The median age at transplantation was 14.0 years (interquartile range [IQR], 11.2-16.1 years); patients were followed up for a median of 5.4 years (IQR, 1.0-10.9 years) after LT. Overall patient survival rates were high with 87% (1-year survival), 84% (5-year survival), and 81% (10-year survival); survival rates increased considerably with the calendar year (P < 0.001). Early age at LT, living donation, and histidine tryptophan ketoglutarate preservation liquid were identified as risk factors for poor patient survival in the multivariate analysis. LT is an excellent treatment option for pediatric patients with WD and associated end-stage liver disease. Longterm outcome in these patients is similar to other pediatric causes for LT. Overall patient and graft survival rates improved considerably over the last decades. To improve future research in the field, the vast variability of allocation strategies should be harmonized and a generally accepted definition or discrimination of acute versus chronic WD needs to be found.
650    _2
$a mladiství $7 D000293
650    _2
$a věkové faktory $7 D000367
650    _2
$a příčina smrti $7 D002423
650    _2
$a dítě $7 D002648
650    _2
$a konečné stadium selhání jater $x diagnóza $x mortalita $x chirurgie $7 D058625
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a disparity zdravotní péče $7 D054625
650    _2
$a hepatolentikulární degenerace $x diagnóza $x mortalita $x chirurgie $7 D006527
650    _2
$a lidé $7 D006801
650    12
$a transplantace jater $x škodlivé účinky $x mortalita $7 D016031
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a registrace $7 D012042
650    _2
$a retrospektivní studie $7 D012189
650    _2
$a rizikové faktory $7 D012307
650    _2
$a časové faktory $7 D013997
650    _2
$a výsledek terapie $7 D016896
651    _2
$a Evropa $x epidemiologie $7 D005060
655    _2
$a časopisecké články $7 D016428
655    _2
$a multicentrická studie $7 D016448
700    1_
$a Karch, André $u Research Group Epidemiological and Statistical Methods, Helmholtz Center for Infection Research, Braunschweig, Germany. German Center for Infection Research, Hannover-Braunschweig, Germany.
700    1_
$a Adam, René $u European Liver Transplant Registry. AP-HP Hôpital Paul Brousse, Université Paris-Sud, Center Hépato-Biliaire, INSERM U 935, Villejuif, France.
700    1_
$a Polak, Wojciech G $u Erasmus University Rotterdam, Rotterdam, the Netherlands.
700    1_
$a Karam, Vincent $u European Liver Transplant Registry. AP-HP Hôpital Paul Brousse, Université Paris-Sud, Center Hépato-Biliaire, INSERM U 935, Villejuif, France.
700    1_
$a Mirza, Darius $u Liver Unit, Elizabeth Hospital Birmingham, University Hospitals Birmingham National Health Service Foundation Trust, Birmingham, United Kingdom.
700    1_
$a O'Grady, John G., $u Institute of Liver Studies, King's College Hospital, London, United Kingdom. $d 1955- $7 xx0305025
700    1_
$a Klempnauer, Jürgen $u General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany.
700    1_
$a Reding, Raymond $u Cliniques Universitaires Saint-Luc, Brussels, Belgium.
700    1_
$a Kalicinski, Piotr $u Department of Pediatric and Transplant Surgery, Children's Memorial Health Institute, Warsaw, Poland.
700    1_
$a Coker, Ahmet $u Department of Gastroenterology, Bozyaka Training and Research Hospital, Izmir, Turkey.
700    1_
$a Trunecka, Pavel $u Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
700    1_
$a Astarcioglu, Ibrahim $u HPB Surgery and Liver Transplantation Unit, Department of General Surgery, School of Medicine, Dokuz Eylul University, Inciralti, İzmir, Turkey.
700    1_
$a Jacquemin, Emmanual $u AP-HP Hôpital Paul Brousse, Université Paris-Sud, Center Hépato-Biliaire, INSERM U 935, Villejuif, France.
700    1_
$a Pratschke, Johann $u Department of Surgery, Charite, Berlin, Germany.
700    1_
$a Paul, Andreas $u Department of General and Transplant Surgery, University Hospital Essen, Essen, Germany.
700    1_
$a Popescu, Irinel $u Department of General Surgery and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania.
700    1_
$a Schneeberger, Stefan $u Department of Visceral, Transplant and Thoracic Surgery, Center of Operative Medicine, Innsbruck Medical University, Innsbruck, Austria.
700    1_
$a Boillot, Oliver $u Liver Transplant Unit, Edouard Herriot Hospital, Lyon, France.
700    1_
$a Fischer, Lutz $u Department of Hepatobiliary Surgery and Visceral Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
700    1_
$a Mikolajczyk, Rafael T $u Research Group Epidemiological and Statistical Methods, Helmholtz Center for Infection Research, Braunschweig, Germany. German Center for Infection Research, Hannover-Braunschweig, Germany.
700    1_
$a Baumann, Ulrich $u Division of Pediatric Gastroenterology and Hepatology, Departments of Pediatric Kidney, Liver, and Metabolic Diseases, Hannover, Germany.
700    1_
$a Duvoux, Christophe $u Department of Hepatology and Liver Transplant Unit, AP-HP Henri Mondor Hospital, Paris Est University, Créteil, France.
710    2_
$a for all European Liver Transplant Registry contributing centers and the European Liver Intestine Transplant Association
773    0_
$w MED00005487 $t Liver transplantation $x 1527-6473 $g Roč. 24, č. 9 (2018), s. 1186-1198
856    41
$u https://pubmed.ncbi.nlm.nih.gov/30021057 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20190813 $b ABA008
991    __
$a 20230808090922 $b ABA008
999    __
$a ok $b bmc $g 1433465 $s 1066776
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 24 $c 9 $d 1186-1198 $e - $i 1527-6473 $m Liver transplantation $n Liver Transpl $x MED00005487
LZP    __
$a Pubmed-20190813
Zpět

Najít záznam

Citační ukazatele

Možnosti archivace