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Flavonoid Glycosides from Endemic Bulgarian Astragalus aitosensis (Ivanisch.)

H. Vasilev, S. Ross, K. Šmejkal, P. Maršík, D. Jankovská, J. Havlík, O. Veselý,

. 2019 ; 24 (7) : . [pub] 20190411

Jazyk angličtina Země Švýcarsko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc19034635

Grantová podpora
16-07193S Grantová Agentura České Republiky
LD14079 European Cooperation in Science and Technology
20172031 CIGA
30016/672 Deutsche Bundesstiftung Umwelt

Astragalus is a very interesting plant genus, well-known for its content of flavonoids, triterpenes and polysaccharides. Its secondary metabolites are described as biologically active compounds showing several activities, e.g., immunomodulating, antibacterial, antiviral and hepatoprotective. This inspired us to analyze the Bulgarian endemic A. aitosensis (Ivanisch.) to obtain deeper information about its phenolic components. We used extensive chromatographic separation of A. aitosensis extract to obtain seven phenolic compounds (1-7), which were identified using combined LC-MS and NMR spectral studies. The 1D and 2D NMR analyses and HR-MS allowed us to resolve the structures of known compounds 5-7 as isorhamnetin-3-O-robinobioside, isorhamnetin-3-O-(2,6-di-O-α-rhamno-pyranosyl-β-galactopyranoside), and alangiflavoside, respectively, and further comparison of these spectral data with available literature helped us with structural analysis of newly described flavonoid glycosides 1-4. These were described in plant source for the first time.

Citace poskytuje Crossref.org

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