-
Je něco špatně v tomto záznamu ?
Automated Family-Wide Annotation of Secondary Structure Elements
A. Midlik, I. Hutařová Vařeková, J. Hutař, TR. Moturu, V. Navrátilová, J. Koča, K. Berka, R. Svobodová Vařeková,
Methods in molecular biology.
2019 ;
1958 (-) :
47-71.
[pub] -
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, práce podpořená grantem
Perzistentní odkaz
https://www.medvik.cz/link/bmc19034665
- MeSH
- algoritmy MeSH
- aminokyselinové motivy * MeSH
- anotace sekvence metody MeSH
- katalytická doména genetika MeSH
- proteiny chemie genetika MeSH
- software MeSH
- výpočetní biologie metody MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Secondary structure elements (SSEs) are inherent parts of protein structures, and their arrangement is characteristic for each protein family. Therefore, annotation of SSEs can facilitate orientation in the vast number of homologous structures which is now available for many protein families. It also provides a way to identify and annotate the key regions, like active sites and channels, and subsequently answer the key research questions, such as understanding of molecular function and its variability.This chapter introduces the concept of SSE annotation and describes the workflow for obtaining SSE annotation for the members of a selected protein family using program SecStrAnnotator.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc19034665
- 003
- CZ-PrNML
- 005
- 20191014131909.0
- 007
- ta
- 008
- 191007s2019 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1007/978-1-4939-9161-7_3 $2 doi
- 035 __
- $a (PubMed)30945213
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Midlik, Adam $u CEITEC-Central European Institute of Technology, Masaryk University, Brno, Czech Republic. midlik@mail.muni.cz. Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic. midlik@mail.muni.cz.
- 245 10
- $a Automated Family-Wide Annotation of Secondary Structure Elements / $c A. Midlik, I. Hutařová Vařeková, J. Hutař, TR. Moturu, V. Navrátilová, J. Koča, K. Berka, R. Svobodová Vařeková,
- 520 9_
- $a Secondary structure elements (SSEs) are inherent parts of protein structures, and their arrangement is characteristic for each protein family. Therefore, annotation of SSEs can facilitate orientation in the vast number of homologous structures which is now available for many protein families. It also provides a way to identify and annotate the key regions, like active sites and channels, and subsequently answer the key research questions, such as understanding of molecular function and its variability.This chapter introduces the concept of SSE annotation and describes the workflow for obtaining SSE annotation for the members of a selected protein family using program SecStrAnnotator.
- 650 _2
- $a algoritmy $7 D000465
- 650 12
- $a aminokyselinové motivy $7 D020816
- 650 _2
- $a katalytická doména $x genetika $7 D020134
- 650 _2
- $a výpočetní biologie $x metody $7 D019295
- 650 _2
- $a anotace sekvence $x metody $7 D058977
- 650 _2
- $a proteiny $x chemie $x genetika $7 D011506
- 650 _2
- $a software $7 D012984
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Hutařová Vařeková, Ivana $u CEITEC-Central European Institute of Technology, Masaryk University, Brno, Czech Republic. Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic. Faculty of Informatics, Masaryk University, Brno, Czech Republic.
- 700 1_
- $a Hutař, Jan $u CEITEC-Central European Institute of Technology, Masaryk University, Brno, Czech Republic. Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic.
- 700 1_
- $a Moturu, Taraka Ramji $u CEITEC-Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
- 700 1_
- $a Navrátilová, Veronika $u Faculty of Science, Department of Physical Chemistry, Regional Centre of Advanced Technologies and Materials, Palacký University, Olomouc, Czech Republic.
- 700 1_
- $a Koča, Jaroslav $u CEITEC-Central European Institute of Technology, Masaryk University, Brno, Czech Republic. Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic.
- 700 1_
- $a Berka, Karel $u Faculty of Science, Department of Physical Chemistry, Regional Centre of Advanced Technologies and Materials, Palacký University, Olomouc, Czech Republic.
- 700 1_
- $a Svobodová Vařeková, Radka $u CEITEC-Central European Institute of Technology, Masaryk University, Brno, Czech Republic. Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic.
- 773 0_
- $w MED00180389 $t Methods in molecular biology (Clifton, N.J.) $x 1940-6029 $g Roč. 1958, č. - (2019), s. 47-71
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/30945213 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20191007 $b ABA008
- 991 __
- $a 20191014132333 $b ABA008
- 999 __
- $a ok $b bmc $g 1451325 $s 1073215
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2019 $b 1958 $c - $d 47-71 $e - $i 1940-6029 $m Methods in molecular biology $n Methods Mol Biol $x MED00180389
- LZP __
- $a Pubmed-20191007
