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A standardised diagnostic approach to pituitary neuroendocrine tumours (PitNETs): a European Pituitary Pathology Group (EPPG) proposal

C. Villa, A. Vasiljevic, ML. Jaffrain-Rea, O. Ansorge, S. Asioli, V. Barresi, L. Chinezu, MP. Gardiman, A. Lania, AM. Lapshina, L. Poliani, L. Reiniger, A. Righi, W. Saeger, J. Soukup, M. Theodoropoulou, S. Uccella, J. Trouillas, F. Roncaroli,

. 2019 ; 475 (6) : 687-692. [pub] 20191002

Language English Country Germany

Document type Journal Article, Review

E-resources Online Full text

NLK ProQuest Central from 2003-01-01 to 1 year ago
Medline Complete (EBSCOhost) from 2011-01-01 to 1 year ago
Nursing & Allied Health Database (ProQuest) from 2003-01-01 to 1 year ago
Health & Medicine (ProQuest) from 2003-01-01 to 1 year ago

The 2017 World Health Organization (WHO) classification proposes to type and subtype primary adenohypophyseal tumours according to their cell lineages with the aim to establish more uniform tumour groups. The definition of atypical adenoma was removed in favour of high-risk adenoma, and the assessment of proliferative activity and invasion was recommended to diagnose aggressive tumours. Recently, the International Pituitary Pathology Club proposed to replace adenoma with the term of pituitary neuroendocrine tumour (PitNET) to better reflect the similarities between adenohypophyseal and neuroendocrine tumours of other organs. The European Pituitary Pathology Group (EPPG) endorses this terminology and develops practical recommendations for standardised reports of PitNETs that are addressed to histo- and neuropathologists. This brief report presents the results of EPPG's consensus for the reporting of PitNETs and proposes a diagnostic algorithm.

1st Department of Pathology and Experimental Cancer Research Semmelweis University Budapest Hungary

Department of Biomedical and Neuromuscular Sciences Section of Anatomic Pathology 'M Malpighi' at Bellaria Hospital University of Bologna Bologna Italy Pituitary Unit Center for the Diagnosis and Treatment of Hypothalamic and Pituitary Diseases IRCCS Istituto delle Scienze Neurologiche di Bologna Bologna Italy

Department of Biotechnological and Applied Clinical Sciences University of L'Aquila L'Aquila Italy Neuromed Institute IRCCS Pozzilli Italy

Department of Diagnostics and Public Health University of Verona Verona Italy

Department of Fundamental Pathomorphology Endocrine Research Center Ministry of Health of Russia Moscow Russia

Department of Histology Pharmacy Sciences and Technology of Tirgu Mures University of Medicine Târgu Mureș Romania

Department of Medicine DIMED Surgical Pathology and Cytopathology Unit University Hospital of Padova Padova Italy

Department of Molecular and Translational Medicine University of Brescia Brescia Italy

Department of Pathological Cytology and Anatomy Foch Hospital 40 rue Worth 92151 Suresnes France INSERM U1016 CNRS UMR 8104 Cochin Institute Paris Descartes University 24 rue du faubourg Saint Jacques 75014 Paris France Department of Endocrinology CHU de Liège University of Liège Sart Tilman B35 4000 Liège Belgium

Department of Pathology Rizzoli Institute Bologna Italy

Division of Neuroscience and Experimental Psychology School of Biological Sciences Faculty of Biology Medicine and Health University of Manchester Manchester UK

Endocrinology Unit Department of Biomedical Sciences Humanitas University and Humanitas Research Hospital Rozzano Italy

Institute of Neuropathology University Medical Center Hamburg Eppendorf Hamburg Germany

Medizinische Klinik und Poliklinik 4 Klinikum der Universität München Ludwig Maximilians Universität München Munich Germany

Nuffield Department of Clinical Neurosciences University of Oxford Oxford OX3 9DU UK

The Fingerland Department of Pathology University Hospital and Faculty of Medicine Hradec Kralove Charles University Sokolska 581 500 05 Hradec Kralove Czech Republic

Unit of Pathology Department of Medicine and Surgery University of Insubria Varese Italy

Université de Lyon 1 Université de Lyon F 69000 Lyon France Faculté de Médecine Lyon Est F 69372 Lyon France

Université de Lyon 1 Université de Lyon F 69000 Lyon France Faculté de Médecine Lyon Est F 69372 Lyon France Centre de Recherche en Cancérologie de Lyon INSERM U1052 CNRS UMR5286 Université de Lyon Lyon France Centre de Pathologie et de Neuropathologie Est Groupement Hospitalier Est Hospices Civils de Lyon Bron France

References provided by Crossref.org

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