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Spontaneous adenocarcinoma of the gas gland in Nothobranchius fishes
I. Dyková, R. Blažek, K. Součková, M. Reichard, O. Slabý,
Language English Country Germany
Document type Journal Article
NLK
Free Medical Journals
from 1985 to 5 years ago
Freely Accessible Science Journals
from 1985 to 4 years ago
PubMed
32132273
DOI
10.3354/dao03437
Knihovny.cz E-resources
- MeSH
- Adenocarcinoma * veterinary MeSH
- Cyprinodontiformes * MeSH
- Longevity MeSH
- Aging MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
Nothobranchius fishes (Cyprinodontiformes), known for their genetically encoded extremely compressed lifespan, are considered an excellent vertebrate model for the research of aging. Unlike the rapid accumulation of data concerning their biology, ecology and genome, knowledge of their age-related diseases, including tumours, is still very limited. This Note reports spontaneous neoplastic lesions in the swim bladder gas glands of Nothobranchius furzeri, N. kadleci and N. orthonotus. Based on light and transmission electron microscopy, the neoplastic proliferation of gas gland cells was classified as adenocarcinoma. There was a concurrent proliferation of haemopoietic cells in the kidney interstitium in all individuals diagnosed with this type of primary neoplasia.
References provided by Crossref.org
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