-
Something wrong with this record ?
Babesia Life Cycle - When Phylogeny Meets Biology
M. Jalovecka, D. Sojka, M. Ascencio, L. Schnittger,
Language English Country Great Britain
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
- MeSH
- Babesia classification genetics growth & development MeSH
- Babesiosis parasitology MeSH
- Phylogeny * MeSH
- Humans MeSH
- Piroplasmida classification genetics growth & development MeSH
- Genes, Protozoan genetics MeSH
- Life Cycle Stages genetics MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments.
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc20022772
- 003
- CZ-PrNML
- 005
- 20201214124758.0
- 007
- ta
- 008
- 201125s2019 xxk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.pt.2019.01.007 $2 doi
- 035 __
- $a (PubMed)30733093
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxk
- 100 1_
- $a Jalovecka, Marie $u Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, CZ-370 05 Ceske Budejovice, Czech Republic; Faculty of Science, University of South Bohemia, CZ-370 05 Ceske Budejovice, Czech Republic. Electronic address: jalovecka@paru.cas.cz.
- 245 10
- $a Babesia Life Cycle - When Phylogeny Meets Biology / $c M. Jalovecka, D. Sojka, M. Ascencio, L. Schnittger,
- 520 9_
- $a Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments.
- 650 _2
- $a zvířata $7 D000818
- 650 _2
- $a Babesia $x klasifikace $x genetika $x růst a vývoj $7 D001403
- 650 _2
- $a babezióza $x parazitologie $7 D001404
- 650 _2
- $a protozoální geny $x genetika $7 D017125
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a stadia vývoje $x genetika $7 D008018
- 650 12
- $a fylogeneze $7 D010802
- 650 _2
- $a Piroplasmida $x klasifikace $x genetika $x růst a vývoj $7 D016792
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 655 _2
- $a přehledy $7 D016454
- 700 1_
- $a Sojka, Daniel $u Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, CZ-370 05 Ceske Budejovice, Czech Republic.
- 700 1_
- $a Ascencio, Mariano $u Instituto de Patobiología Veterinaria, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA-Castelar, Los Reseros y Nicolas Repetto s/n, Hurlingham 1686, Argentina; National Council of Scientific and Technological Research (CONICET), Ciudad Autónoma de Buenos Aires C1033AAJ, Argentina.
- 700 1_
- $a Schnittger, Leonhard $u Instituto de Patobiología Veterinaria, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA-Castelar, Los Reseros y Nicolas Repetto s/n, Hurlingham 1686, Argentina; National Council of Scientific and Technological Research (CONICET), Ciudad Autónoma de Buenos Aires C1033AAJ, Argentina.
- 773 0_
- $w MED00006043 $t Trends in parasitology $x 1471-5007 $g Roč. 35, č. 5 (2019), s. 356-368
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/30733093 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20201125 $b ABA008
- 991 __
- $a 20201214124758 $b ABA008
- 999 __
- $a ok $b bmc $g 1595091 $s 1113448
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2019 $b 35 $c 5 $d 356-368 $e 20190204 $i 1471-5007 $m Trends in parasitology $n Trends Parasitol $x MED00006043
- LZP __
- $a Pubmed-20201125
