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Genetic T-type calcium channelopathies
N. Weiss, GW. Zamponi,
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, přehledy
NLK
ProQuest Central
od 1994-01-01 do Před 6 měsíci
Health & Medicine (ProQuest)
od 1994-01-01 do Před 6 měsíci
- MeSH
- kanálopatie genetika metabolismus MeSH
- lidé MeSH
- mutace MeSH
- vápníkové kanály genetika MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
T-type channels are low-voltage-activated calcium channels that contribute to a variety of cellular and physiological functions, including neuronal excitability, hormone and neurotransmitter release as well as developmental aspects. Several human conditions including epilepsy, autism spectrum disorders, schizophrenia, motor neuron disorders and aldosteronism have been traced to variations in genes encoding T-type channels. In this short review, we present the genetics of T-type channels with an emphasis on structure-function relationships and associated channelopathies.
Citace poskytuje Crossref.org
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