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Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future
P. Hofman, M. Ilié, E. Chamorey, P. Brest, R. Schiappa, V. Nakache, M. Antoine, M. Barberis, H. Begueret, F. Bibeau, C. Bonnetaud, P. Boström, P. Brousset, L. Bubendorf, L. Carvalho, G. Cathomas, A. Cazes, L. Chalabreysse, MP. Chenard, MC. Copin,...
Language English Country Great Britain
Document type Journal Article, Multicenter Study
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PubMed Central
from 2016
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- MeSH
- Biological Specimen Banks organization & administration statistics & numerical data MeSH
- COVID-19 epidemiology prevention & control virology MeSH
- Disease Outbreaks MeSH
- Pathology, Clinical methods statistics & numerical data trends MeSH
- Humans MeSH
- Pathology, Molecular methods statistics & numerical data trends MeSH
- Thoracic Diseases diagnosis therapy MeSH
- Specimen Handling methods statistics & numerical data MeSH
- Containment of Biohazards statistics & numerical data MeSH
- Pandemics MeSH
- Forecasting MeSH
- Surveys and Questionnaires * MeSH
- SARS-CoV-2 isolation & purification physiology MeSH
- Clinical Laboratory Services statistics & numerical data trends MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Geographicals
- Europe MeSH
BACKGROUND: This study evaluated the consequences in Europe of the COVID-19 outbreak on pathology laboratories orientated toward the diagnosis of thoracic diseases. MATERIALS AND METHODS: A survey was sent to 71 pathology laboratories from 21 European countries. The questionnaire requested information concerning the organization of biosafety, the clinical and molecular pathology, the biobanking, the workload, the associated research into COVID-19, and the organization of education and training during the COVID-19 crisis, from 15 March to 31 May 2020, compared with the same period in 2019. RESULTS: Questionnaires were returned from 53/71 (75%) laboratories from 18 European countries. The biosafety procedures were heterogeneous. The workload in clinical and molecular pathology decreased dramatically by 31% (range, 3%-55%) and 26% (range, 7%-62%), respectively. According to the professional category, between 28% and 41% of the staff members were not present in the laboratories but did teleworking. A total of 70% of the laboratories developed virtual meetings for the training of residents and junior pathologists. During the period of study, none of the staff members with confirmed COVID-19 became infected as a result of handling samples. CONCLUSIONS: The COVID-19 pandemic has had a strong impact on most of the European pathology laboratories included in this study. Urgent implementation of several changes to the organization of most of these laboratories, notably to better harmonize biosafety procedures, was noted at the onset of the pandemic and maintained in the event of a new wave of infection occurring in Europe.
Centre for Oncological Research University of Antwerp Antwerp Belgium
Department of Cellular Pathology University Hospital Southampton NHS Foundation Trust Southampton UK
Department of Oncology University of Torino Torino Italy
Department of Pathology Aberdeen Royal Infirmary Aberdeen UK
Department of Pathology Amsterdam University Medical Centres Location VUmc Amsterdam The Netherlands
Department of Pathology and Molecular Pathology Centre Jean Perrin Clermont Ferrand France
Department of Pathology Bichat Hospital AP HP Inserm UMR 1152 Université de Paris Paris France
Department of Pathology Centre Hospitalier Le Mans France
Department of Pathology CHU de Caen Université de Caen Normandie Caen France
Department of Pathology Complejo Hospitalario de Navarra Pamplona Spain
Department of Pathology Erasme Hospital Université Libre de Bruxelles Brussels Belgium
Department of Pathology Groupement Hospitalier Est Hospices Civils de Lyon Lyon France
Department of Pathology Hôpital Européen Georges Pompidou AP HP Université de Paris Paris France
Department of Pathology Hôpital Nord AP HM Aix Marseille University Marseille France
Department of Pathology Hôpital Tenon AP HP Paris France
Department of Pathology Inserm 1245 Rouen University Hospital Normandy University Rouen France
Department of Pathology Institut Mutualiste Montsouris Paris France
Department of Pathology IUC T Oncopole Inserm U1037 CRCT Université de Toulouse Toulouse France
Department of Pathology Karolinska University Hospital Stockholm Sweden
Department of Pathology Marie Lannelongue Hospital Le Plessis Robinson France
Department of Pathology Turku University Hospital Turku Finland
Department of Pathology University Clinic Golnik Golnik Slovenia
Department of Pathology University Hospital of Bordeaux Bordeaux France
Department of Pathology University Hospital of Saint Etienne Saint Etienne France
Department of Pathology University Hospital of Strasbourg Strasbourg France
Department of Pathology University Hospital of Tours Tours France
Department of Pathology University of Oradea Oradea Romania
Department of Pathology Vall d'Hebron University Hospital Barcelona Spain
Department of Pathology Victor Babes University of Medicine and Pharmacy Timisoara Romania
Department of Pneumology FHU OncoAge Louis Pasteur Hospital IRCAN Université Côte d'Azur Nice France
Department of Public Health University of Naples Frederico 2 Naples Italy
Department of Thoracic Surgery FHU OnoAge Louis Pasteur Hospital University Côte d'Azur Nice France
Epidemiology and Biostatistics Unit Centre Antoine Lacassagne Université Côte d'Azur Nice France
Institut de Pathologie CHU Lille Université de Lille Lille France
Institute of Pathology Cantonal Hospital Baselland Liestal Switzerland
Institute of Pathology Medical University of Graz Graz Austria
Institute of Pathology University Hospital Essen Essen Germany
Institute of Pathology University Hospital Ostrava Ostrava Czech Republic
Institute of Pathology University of Regensburg Regensburg Germany
Laboratory of Pathology Finnish Institute of Occupational Health Helsinki Finland
Liverpool University Hospitals Royal Liverpool University Hospital Liverpool UK
Pulmonary Pathology Department Gregorio Marañon University Hospital Madrid Spain
Team 4 IRCAN INSERM CNRS Centre Antoine Lacassagne Université Côte d'Azur Nice France
Unit of Pathology Azienda Ospedaliera dei Colli Monaldi Cotugno CTO Naples Italy
References provided by Crossref.org
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- $a BACKGROUND: This study evaluated the consequences in Europe of the COVID-19 outbreak on pathology laboratories orientated toward the diagnosis of thoracic diseases. MATERIALS AND METHODS: A survey was sent to 71 pathology laboratories from 21 European countries. The questionnaire requested information concerning the organization of biosafety, the clinical and molecular pathology, the biobanking, the workload, the associated research into COVID-19, and the organization of education and training during the COVID-19 crisis, from 15 March to 31 May 2020, compared with the same period in 2019. RESULTS: Questionnaires were returned from 53/71 (75%) laboratories from 18 European countries. The biosafety procedures were heterogeneous. The workload in clinical and molecular pathology decreased dramatically by 31% (range, 3%-55%) and 26% (range, 7%-62%), respectively. According to the professional category, between 28% and 41% of the staff members were not present in the laboratories but did teleworking. A total of 70% of the laboratories developed virtual meetings for the training of residents and junior pathologists. During the period of study, none of the staff members with confirmed COVID-19 became infected as a result of handling samples. CONCLUSIONS: The COVID-19 pandemic has had a strong impact on most of the European pathology laboratories included in this study. Urgent implementation of several changes to the organization of most of these laboratories, notably to better harmonize biosafety procedures, was noted at the onset of the pandemic and maintained in the event of a new wave of infection occurring in Europe.
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