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Wastewater-Based Epidemiology as an Early Warning System for the Spreading of SARS-CoV-2 and Its Mutations in the Population

T. Mackuľak, M. Gál, V. Špalková, M. Fehér, K. Briestenská, M. Mikušová, K. Tomčíková, M. Tamáš, A. Butor Škulcová

. 2021 ; 18 (11) : . [pub] 20210525

Language English Country Switzerland

Document type Journal Article, Research Support, Non-U.S. Gov't, Review

Persistent link   https://www.medvik.cz/link/bmc21018566

Grant support
17-0119 Agentúra na Podporu Výskumu a Vývoja
17-0183 Agentúra na Podporu Výskumu a Vývoja
PP-COVID-20-0019 Agentúra na Podporu Výskumu a Vývoja
APVV-19-0250 Agentúra na Podporu Výskumu a Vývoja
831644 Horizon 2020 Framework Programme
313011ASS8 European Regional Development Fund
Microplastics in waters of Slovakia - monitoring and possibilities of use innovative processes for their removal Slovenská technická univerzita v Bratislave
Hospitals and music festivals as point sources of micropollutants in surface water and effective options for their removal Slovenská technická univerzita v Bratislave
Monitoring and removal of SARS-CoV-2 RNA fragments in wastewater using ferrates Slovenská technická univerzita v Bratislave
Households as a potential source of microfibers for the environment Slovenská technická univerzita v Bratislave
CZ.02.1.01/0.0/0.0/16_019/0000845 European Regional Development Fund

New methodologies based on the principle of "sewage epidemiology" have been successfully applied before in the detection of illegal drugs. The study describes the idea of early detection of a virus, e.g., SARS-CoV-2, in wastewater in order to focus on the area of virus occurrence and supplement the results obtained from clinical examination. By monitoring temporal variation in viral loads in wastewater in combination with other analysis, a virus outbreak can be detected and its spread can be suppressed early. The use of biosensors for virus detection also seems to be an interesting application. Biosensors are highly sensitive, selective, and portable and offer a way for fast analysis. This manuscript provides an overview of the current situation in the area of wastewater analysis, including genetic sequencing regarding viral detection and the technological solution of an early warning system for wastewater monitoring based on biosensors.

References provided by Crossref.org

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$a Monitoring and removal of SARS-CoV-2 RNA fragments in wastewater using ferrates $p Slovenská technická univerzita v Bratislave
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