Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Double-layered Nanofibrous Patch for Prevention of Anastomotic Leakage and Peritoneal Adhesions, Experimental Study

J. Rosendorf, M. Klicova, L. Cervenkova, R. Palek, J. Horakova, A. Klapstova, P. Hosek, V. Moulisova, L. Bednar, V. Tegl, O. Brzon, Z. Tonar, V. Treska, D. Lukas, V. Liska

. 2021 ; 35 (2) : 731-741. [pub] -

Jazyk angličtina Země Řecko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc21019137

BACKGROUND/AIM: Anastomotic leakage is a feared complication in colorectal surgery. Postoperative peritoneal adhesions can also cause life-threatening conditions. Nanofibrous materials showed their pro-healing properties in various studies. The aim of the study was to evaluate the impact of double-layered nanofibrous materials on anastomotic healing and peritoneal adhesions formation. MATERIALS AND METHODS: Two versions of double-layered materials from polycaprolactone and polyvinyl alcohol were applied on defective anastomosis on the small intestine of healthy pigs. The control group remained with uncovered defect. Tissue specimens were subjected to histological analysis and adhesion scoring after 3 weeks of observation. RESULTS: The wound healing was inferior in the experimental groups, however, no anastomotic leakage was observed and the applied material always kept covering the defect. The extent of adhesions was larger in the experimental groups. CONCLUSION: Nanofibrous materials may prevent anastomotic leakage but delay healing.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc21019137
003      
CZ-PrNML
005      
20210830100721.0
007      
ta
008      
210728s2021 gr f 000 0|eng||
009      
AR
024    7_
$a 10.21873/invivo.12314 $2 doi
035    __
$a (PubMed)33622866
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a gr
100    1_
$a Rosendorf, Jachym $u Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic; jachymrosendorf@gmail.com $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
245    10
$a Double-layered Nanofibrous Patch for Prevention of Anastomotic Leakage and Peritoneal Adhesions, Experimental Study / $c J. Rosendorf, M. Klicova, L. Cervenkova, R. Palek, J. Horakova, A. Klapstova, P. Hosek, V. Moulisova, L. Bednar, V. Tegl, O. Brzon, Z. Tonar, V. Treska, D. Lukas, V. Liska
520    9_
$a BACKGROUND/AIM: Anastomotic leakage is a feared complication in colorectal surgery. Postoperative peritoneal adhesions can also cause life-threatening conditions. Nanofibrous materials showed their pro-healing properties in various studies. The aim of the study was to evaluate the impact of double-layered nanofibrous materials on anastomotic healing and peritoneal adhesions formation. MATERIALS AND METHODS: Two versions of double-layered materials from polycaprolactone and polyvinyl alcohol were applied on defective anastomosis on the small intestine of healthy pigs. The control group remained with uncovered defect. Tissue specimens were subjected to histological analysis and adhesion scoring after 3 weeks of observation. RESULTS: The wound healing was inferior in the experimental groups, however, no anastomotic leakage was observed and the applied material always kept covering the defect. The extent of adhesions was larger in the experimental groups. CONCLUSION: Nanofibrous materials may prevent anastomotic leakage but delay healing.
650    _2
$a anastomóza chirurgická $x škodlivé účinky $7 D000714
650    12
$a netěsnost anastomózy $x etiologie $x patologie $x prevence a kontrola $7 D057868
650    _2
$a zvířata $7 D000818
650    _2
$a kolon $x patologie $7 D003106
650    12
$a nanovlákna $7 D057139
650    _2
$a prasata $7 D013552
650    _2
$a adheze tkání $x prevence a kontrola $7 D000267
650    _2
$a hojení ran $7 D014945
655    _2
$a časopisecké články $7 D016428
700    1_
$a Klicova, Marketa $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Liberec, Czech Republic
700    1_
$a Cervenkova, Lenka $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic $u Department of Pathology, Third Faculty of Medicine, Charles University, Prague, Czech Republic
700    1_
$a Palek, Richard $u Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
700    1_
$a Horakova, Jana $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Liberec, Czech Republic
700    1_
$a Klapstova, Andrea $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Liberec, Czech Republic
700    1_
$a Hosek, Petr $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
700    1_
$a Moulisova, Vladimira $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
700    1_
$a Bednar, Lukas $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
700    1_
$a Tegl, Vaclav $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic $u Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine in Plzen, Pilsen, Czech Republic
700    1_
$a Brzon, Ondrej $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
700    1_
$a Tonar, Zbynek $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic $u Department of Histology and Embryology, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
700    1_
$a Treska, Vladislav $u Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
700    1_
$a Lukas, David $u Department of Nonwovens and Nanofibrous Materials, Faculty of Textile Engineering, Technical University of Liberec, Liberec, Czech Republic $u Department of Chemistry, Faculty of Science, Humanities and Education, Technical University of Liberec, Liberec, Czech Republic
700    1_
$a Liska, Vaclav $u Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic $u Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
773    0_
$w MED00175831 $t In vivo (Athens, Greece) $x 1791-7549 $g Roč. 35, č. 2 (2021), s. 731-741
856    41
$u https://pubmed.ncbi.nlm.nih.gov/33622866 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20210728 $b ABA008
991    __
$a 20210830100721 $b ABA008
999    __
$a ok $b bmc $g 1690053 $s 1139583
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2021 $b 35 $c 2 $d 731-741 $e - $i 1791-7549 $m In Vivo $n In Vivo $x MED00175831
LZP    __
$a Pubmed-20210728

Najít záznam

Citační ukazatele

Možnosti archivace