Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Current perspective on eicosanoids in asthma and allergic diseases: EAACI Task Force consensus report, part I

M. Sokolowska, GE. Rovati, Z. Diamant, E. Untersmayr, J. Schwarze, Z. Lukasik, F. Sava, A. Angelina, O. Palomares, CA. Akdis, L. O'Mahony, M. Sanak, SE. Dahlen, G. Woszczek

. 2021 ; 76 (1) : 114-130. [pub] -

Jazyk angličtina Země Dánsko

Typ dokumentu časopisecké články, práce podpořená grantem, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc21019494

Grantová podpora
G0900536 Medical Research Council - United Kingdom
G1000758 Medical Research Council - United Kingdom
MC_PC_15031 Medical Research Council - United Kingdom

Eicosanoids are biologically active lipid mediators, comprising prostaglandins, leukotrienes, thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to asthma, allergies, and allied diseases. Prostaglandins and leukotrienes are the most studied eicosanoids and established inducers of airway pathophysiology including bronchoconstriction and airway inflammation. Drugs inhibiting the synthesis of lipid mediators or their effects, such as leukotriene synthesis inhibitors, leukotriene receptors antagonists, and more recently prostaglandin D2 receptor antagonists, have been shown to modulate features of asthma and allergic diseases. This review, produced by an European Academy of Allergy and Clinical Immunology (EAACI) task force, highlights our current understanding of eicosanoid biology and its role in mediating human pathology, with a focus on new findings relevant for clinical practice, development of novel therapeutics, and future research opportunities.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc21019494
003      
CZ-PrNML
005      
20210830101058.0
007      
ta
008      
210728s2021 dk f 000 0|eng||
009      
AR
024    7_
$a 10.1111/all.14295 $2 doi
035    __
$a (PubMed)32279330
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a dk
100    1_
$a Sokolowska, Milena $u Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland $u Christine Kühne - Center for Allergy Research and Education (CK-CARE), Davos, Switzerland
245    10
$a Current perspective on eicosanoids in asthma and allergic diseases: EAACI Task Force consensus report, part I / $c M. Sokolowska, GE. Rovati, Z. Diamant, E. Untersmayr, J. Schwarze, Z. Lukasik, F. Sava, A. Angelina, O. Palomares, CA. Akdis, L. O'Mahony, M. Sanak, SE. Dahlen, G. Woszczek
520    9_
$a Eicosanoids are biologically active lipid mediators, comprising prostaglandins, leukotrienes, thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to asthma, allergies, and allied diseases. Prostaglandins and leukotrienes are the most studied eicosanoids and established inducers of airway pathophysiology including bronchoconstriction and airway inflammation. Drugs inhibiting the synthesis of lipid mediators or their effects, such as leukotriene synthesis inhibitors, leukotriene receptors antagonists, and more recently prostaglandin D2 receptor antagonists, have been shown to modulate features of asthma and allergic diseases. This review, produced by an European Academy of Allergy and Clinical Immunology (EAACI) task force, highlights our current understanding of eicosanoid biology and its role in mediating human pathology, with a focus on new findings relevant for clinical practice, development of novel therapeutics, and future research opportunities.
650    12
$a bronchiální astma $x etiologie $7 D001249
650    _2
$a konsensus $7 D032921
650    _2
$a ikosanoidy $7 D015777
650    _2
$a lidé $7 D006801
650    12
$a alergie $7 D006967
650    _2
$a leukotrieny $7 D015289
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
655    _2
$a přehledy $7 D016454
700    1_
$a Rovati, G Enrico $u Department of Pharmaceutical Sciences, University of Milan, Milan, Italy
700    1_
$a Diamant, Zuzana $u Department of Respiratory Medicine & Allergology, Skane University Hospital, Lund, Sweden $u Department of Respiratory Medicine, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic
700    1_
$a Untersmayr, Eva $u Institute of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
700    1_
$a Schwarze, Jargen $u Child Life and Health and Centre for Inflammation Research, The University of Edinburgh, Edinburgh, UK
700    1_
$a Lukasik, Zuzanna $u Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
700    1_
$a Sava, Florentina $u London North Genomic Laboratory Hub, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK
700    1_
$a Angelina, Alba $u Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain
700    1_
$a Palomares, Oscar $u Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain
700    1_
$a Akdis, Cezmi A $u Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland $u Christine Kühne - Center for Allergy Research and Education (CK-CARE), Davos, Switzerland
700    1_
$a O'Mahony, Liam $u Departments of Medicine and Microbiology, APC Microbiome Ireland, University College Cork, Cork, Ireland
700    1_
$a Sanak, Marek $u Department of Medicine, Jagiellonian University Medical College, Krakow, Poland
700    1_
$a Dahlen, Sven-Erik $u Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden $u Centre for Allergy Research, Karolinska Institute, Stockholm, Sweden
700    1_
$a Woszczek, Grzegorz $u MRC/Asthma UK Centre in Allergic Mechanisms of Asthma, School of Immunology & Microbial Sciences, King's College London, London, UK
773    0_
$w MED00009088 $t Allergy $x 1398-9995 $g Roč. 76, č. 1 (2021), s. 114-130
856    41
$u https://pubmed.ncbi.nlm.nih.gov/32279330 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20210728 $b ABA008
991    __
$a 20210830101058 $b ABA008
999    __
$a ok $b bmc $g 1690341 $s 1139940
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2021 $b 76 $c 1 $d 114-130 $e - $i 1398-9995 $m Allergy $n Allergy $x MED00009088
GRA    __
$a G0900536 $p Medical Research Council $2 United Kingdom
GRA    __
$a G1000758 $p Medical Research Council $2 United Kingdom
GRA    __
$a MC_PC_15031 $p Medical Research Council $2 United Kingdom
LZP    __
$a Pubmed-20210728

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace