• Something wrong with this record ?

Contribution of intravenous medication to water and sodium intake in upper and lower gastrointestinal surgical patients

PD. Austin, V. Joskova, A. Patkova, M. Elia

. 2020 ; 78 (-) : 110808. [pub] 20200406

Language English Country United States

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc21020078

Grant support
ICA-CL-2016-02-016 Department of Health - United Kingdom

E-resources Online Full text

NLK ProQuest Central from 2003-01-01 to 2 months ago
Nursing & Allied Health Database (ProQuest) from 2003-01-01 to 2 months ago
Health & Medicine (ProQuest) from 2003-01-01 to 2 months ago
Health Management Database (ProQuest) from 2003-01-01 to 2 months ago
Public Health Database (ProQuest) from 2003-01-01 to 2 months ago

Links

PubMed 32540676
DOI 10.1016/j.nut.2020.110808
Knihovny.cz E-resources

OBJECTIVES: The quantitative importance of prescribed intravenous (IV) medication to water and sodium intake in routine clinical practice is undocumented, with uncertain influence on clinical outcomes. The present study aimed to redress this issue in surgical patients with gastrointestinal problems. METHODS: The prescription and administration of IV medication and fluids were retrospectively reviewed for water and sodium over 24-h periods in 86 patients in upper and lower gastrointestinal surgical wards in two teaching hospitals. Changes over 5 y were assessed in the same two wards using the same methodology. RESULTS: Among 90.7% of patients prescribed IV medication, the median intake was 272 mL water/d (range, 40-2687 mL water/d) and 27 mmol sodium/d (range, 2-420 mmol sodium/d), with no significant difference between hospitals or ward type. In 28.2% of patients receiving any infusates, the only source of water and sodium was IV medication, and in 14.3% of patients, the medication provided more sodium than other infusates. Antibiotic agents and paracetamol accounted for 58.3% of water and 52.3% of sodium in IV medication. Historic data of IV medicine-related water and sodium intake did not differ significantly from current data. The literature suggests that clinical outcomes can be modulated by variations in water and sodium intake well within the range provided by IV medication. CONCLUSION: IV medicine prescriptions, particularly antibiotic agents and paracetamol, can make substantial and clinically relevant contributions to daily water and sodium intake. These contributions have persisted over time and should be considered during routine assessments of fluid balance and interventions aiming to improve clinical outcomes.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc21020078
003      
CZ-PrNML
005      
20210830101702.0
007      
ta
008      
210728s2020 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.nut.2020.110808 $2 doi
035    __
$a (PubMed)32540676
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Austin, Peter D $u Pharmacy Department, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom; Department of Pharmaceutics, School of Pharmacy, University College London, London, United Kingdom; Southampton Pharmacy Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom. Electronic address: Peter.Austin@ouh.nhs.uk
245    10
$a Contribution of intravenous medication to water and sodium intake in upper and lower gastrointestinal surgical patients / $c PD. Austin, V. Joskova, A. Patkova, M. Elia
520    9_
$a OBJECTIVES: The quantitative importance of prescribed intravenous (IV) medication to water and sodium intake in routine clinical practice is undocumented, with uncertain influence on clinical outcomes. The present study aimed to redress this issue in surgical patients with gastrointestinal problems. METHODS: The prescription and administration of IV medication and fluids were retrospectively reviewed for water and sodium over 24-h periods in 86 patients in upper and lower gastrointestinal surgical wards in two teaching hospitals. Changes over 5 y were assessed in the same two wards using the same methodology. RESULTS: Among 90.7% of patients prescribed IV medication, the median intake was 272 mL water/d (range, 40-2687 mL water/d) and 27 mmol sodium/d (range, 2-420 mmol sodium/d), with no significant difference between hospitals or ward type. In 28.2% of patients receiving any infusates, the only source of water and sodium was IV medication, and in 14.3% of patients, the medication provided more sodium than other infusates. Antibiotic agents and paracetamol accounted for 58.3% of water and 52.3% of sodium in IV medication. Historic data of IV medicine-related water and sodium intake did not differ significantly from current data. The literature suggests that clinical outcomes can be modulated by variations in water and sodium intake well within the range provided by IV medication. CONCLUSION: IV medicine prescriptions, particularly antibiotic agents and paracetamol, can make substantial and clinically relevant contributions to daily water and sodium intake. These contributions have persisted over time and should be considered during routine assessments of fluid balance and interventions aiming to improve clinical outcomes.
650    _2
$a tekutinová terapie $7 D005440
650    _2
$a lidé $7 D006801
650    _2
$a retrospektivní studie $7 D012189
650    _2
$a sodík $7 D012964
650    12
$a sodík dietní $7 D012982
650    12
$a voda $7 D014867
655    _2
$a časopisecké články $7 D016428
700    1_
$a Joskova, Vera $u Hospital Pharmacy, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic; Department of Biological and Medical Sciences, Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic
700    1_
$a Patkova, Anna $u Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic
700    1_
$a Elia, Marinos $u Faculty of Medicine, University of Southampton, Southampton, United Kingdom
773    0_
$w MED00003566 $t Nutrition (Burbank, Los Angeles County, Calif.) $x 1873-1244 $g Roč. 78, č. - (2020), s. 110808
856    41
$u https://pubmed.ncbi.nlm.nih.gov/32540676 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20210728 $b ABA008
991    __
$a 20210830101702 $b ABA008
999    __
$a ok $b bmc $g 1690797 $s 1140524
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2020 $b 78 $c - $d 110808 $e 20200406 $i 1873-1244 $m Nutrition $n Nutrition $x MED00003566
GRA    __
$a ICA-CL-2016-02-016 $p Department of Health $2 United Kingdom
LZP    __
$a Pubmed-20210728

Find record

Citation metrics

Archiving options