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Which patients with atrial fibrillation undergo an ablation procedure today in Europe? A report from the ESC-EHRA-EORP Atrial Fibrillation Ablation Long-Term and Atrial Fibrillation General Pilot Registries
RR. Tilz, N. Dagres, E. Arbelo, C. Blomström-Lundqvist, HJ. Crijns, P. Kirchhof, J. Kautzner, PL. Temporelli, C. Laroche, PR. Roberts, S. Pehrson, GYH. Lip, J. Brugada, L. Tavazzi, Atrial Fibrillation Ablation and Atrial Fibrillation Registries...
Language English Country Great Britain
Document type Journal Article, Research Support, Non-U.S. Gov't
NLK
Free Medical Journals
from 1999 to 1 year ago
PubMed Central
from 2008
Open Access Digital Library
from 1999-01-01
Medline Complete (EBSCOhost)
from 1999-01-01
Oxford Journals Open Access Collection
from 1999-01-01
- MeSH
- Anticoagulants MeSH
- Stroke * MeSH
- Atrial Fibrillation * diagnosis epidemiology surgery MeSH
- Ventricular Function, Left MeSH
- Catheter Ablation * adverse effects MeSH
- Humans MeSH
- Registries MeSH
- Risk Factors MeSH
- Stroke Volume MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Europe MeSH
AIMS: Rhythm control management in patients with atrial fibrillation (AF) may be unequal across Europe. The aim of this study was to investigate how selective the patient cohort referred for AF ablation is, as compared to the general AF population in Europe, and to describe the governing mechanisms for such selection. METHODS AND RESULTS: Descriptive comparative statistical analyses of the baseline characteristics were performed between the cohorts of Atrial Fibrillation Ablation Long-Term (ESC EORP AFA-LT) registry, designed to provide a picture of contemporary real-world AF ablation, and the AF population from the AF-General (ESC EORP AF-Gen) pilot registry. Data collection was performed using a web-based system. In the AFA and in the Atrial Fibrillation General (AFG) pilot registries, 3593 and 3049 patients were enrolled, respectively. Patients who underwent AF ablation were younger, more commonly male, and had significantly less comorbidities. Atrial Fibrillation Ablation patients often presented without comorbidities, resulting in a lower risk of stroke (CHA2DS2-VASc ≥5: 2.9% vs. 24.5%, all P < 0.001) and bleeding (HAS-BLED ≥2: 8.5% vs. 40.5%, P < 0.001) but with European Heart Rhythm Association (EHRA) scores >1 and more prevalent AF-related symptoms such as palpitations, fatigue, and weakness (all P < 0.001) as compared to the general AF patients. Atrial Fibrillation Ablation patients were significantly more often male, had higher left ventricular ejection fraction (59.5% vs. 52.4%) and smaller left atrial size on echocardiogram (P < 0.001 each). CONCLUSION: The comparison of the patient cohorts in the AFA and AFG registries showed that AF ablation in European clinical practice is mostly performed in relatively young, symptomatic and relatively healthy patients.
Cardiovascular Research Institute Maastricht Maastricht The Netherlands
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares Madrid Spain
Department of Cardiology Asklepios Klinik St Georg Hamburg Germany
Department of Cardiology Maastricht University Medical Center Maastricht The Netherlands
Department of Cardiology Rigshospitalet University Hospital Copenhagen Denmark
Department of Clinical Medicine Aalborg Thrombosis Research Unit Aalborg University Aalborg Denmark
Department of Electrophysiology Heart Center Leipzig at University of Leipzig Leipzig Germany
Department of Medical Science and Cardiology Uppsala University Uppsala Sweden
Division of Cardiology Istituti Clinici Scientifici Maugeri IRCCS Veruno Italy
DZHK Partner Site Hamburg Kiel Lübeck Berlin Germany
EURObservational Research Programme ESC Sophia Antipolis France
Institute for Clinical and Experimental Medicine Prague Czech Republic
Maria Cecilia Hospital GVM Care and Research Cotignola Italy
University Hospital Southampton NHS Trust Southampton Great Britain
References provided by Crossref.org
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- $a Tilz, Roland Richard $u Department of Cardiology, Angiology and Intensive Care Medicine, University Heart Center, Medical Clinic II, University Hospital Schleswig-Holstein, Ratzeburger Allee 160, 23538 Luebeck, Germany $u Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany $u DZHK (German Center for Cardiovascular Research), Partner Site, Hamburg/Kiel/Lübeck, Berlin, Germany
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- $a AIMS: Rhythm control management in patients with atrial fibrillation (AF) may be unequal across Europe. The aim of this study was to investigate how selective the patient cohort referred for AF ablation is, as compared to the general AF population in Europe, and to describe the governing mechanisms for such selection. METHODS AND RESULTS: Descriptive comparative statistical analyses of the baseline characteristics were performed between the cohorts of Atrial Fibrillation Ablation Long-Term (ESC EORP AFA-LT) registry, designed to provide a picture of contemporary real-world AF ablation, and the AF population from the AF-General (ESC EORP AF-Gen) pilot registry. Data collection was performed using a web-based system. In the AFA and in the Atrial Fibrillation General (AFG) pilot registries, 3593 and 3049 patients were enrolled, respectively. Patients who underwent AF ablation were younger, more commonly male, and had significantly less comorbidities. Atrial Fibrillation Ablation patients often presented without comorbidities, resulting in a lower risk of stroke (CHA2DS2-VASc ≥5: 2.9% vs. 24.5%, all P < 0.001) and bleeding (HAS-BLED ≥2: 8.5% vs. 40.5%, P < 0.001) but with European Heart Rhythm Association (EHRA) scores >1 and more prevalent AF-related symptoms such as palpitations, fatigue, and weakness (all P < 0.001) as compared to the general AF patients. Atrial Fibrillation Ablation patients were significantly more often male, had higher left ventricular ejection fraction (59.5% vs. 52.4%) and smaller left atrial size on echocardiogram (P < 0.001 each). CONCLUSION: The comparison of the patient cohorts in the AFA and AFG registries showed that AF ablation in European clinical practice is mostly performed in relatively young, symptomatic and relatively healthy patients.
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