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Analytical Methods for the Determination of Neuroactive Steroids
M. Kaleta, J. Oklestkova, O. Novák, M. Strnad
Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
Grantová podpora
IGA_PrF_2021_011
Palacky University
No. CZ.02.1.01/0.0/0.0/16_019/0000827
ERDF project "Plants as a tool for sustainable global development"
NLK
Directory of Open Access Journals
od 2011
PubMed Central
od 2011
Europe PubMed Central
od 2011
ProQuest Central
od 2011-01-01
Open Access Digital Library
od 2011-01-01
Open Access Digital Library
od 2011-01-01
Health & Medicine (ProQuest)
od 2011-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2011
PubMed
33918915
DOI
10.3390/biom11040553
Knihovny.cz E-zdroje
- MeSH
- biochemická analýza krve metody MeSH
- hmotnostní spektrometrie metody MeSH
- hormony krev metabolismus MeSH
- imunoanalýza metody MeSH
- lidé MeSH
- neurosteroidy krev metabolismus MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
Neuroactive steroids are a family of all steroid-based compounds, of both natural and synthetic origin, which can affect the nervous system functions. Their biosynthesis occurs directly in the nervous system (so-called neurosteroids) or in peripheral endocrine tissues (hormonal steroids). Steroid hormone levels may fluctuate due to physiological changes during life and various pathological conditions affecting individuals. A deeper understanding of neuroactive steroids' production, in addition to reliable monitoring of their levels in various biological matrices, may be useful in the prevention, diagnosis, monitoring, and treatment of some neurodegenerative and psychiatric diseases. The aim of this review is to highlight the most relevant methods currently available for analysis of neuroactive steroids, with an emphasis on immunoanalytical methods and gas, or liquid chromatography combined with mass spectrometry.
Citace poskytuje Crossref.org
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