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Parthenogenesis as a Solution to Hybrid Sterility: The Mechanistic Basis of Meiotic Distortions in Clonal and Sterile Hybrids
D. Dedukh, Z. Majtánová, A. Marta, M. Pšenička, J. Kotusz, J. Klíma, D. Juchno, A. Boron, K. Janko
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, práce podpořená grantem
NLK
Free Medical Journals
od 1916 do Před 6 měsíci
Freely Accessible Science Journals
od 1916 do Před 1 rokem
Europe PubMed Central
od 1916 do Před 1 rokem
ProQuest Central
od 2004-10-01 do 2020-12-31
Open Access Digital Library
od 1916-01-01
Open Access Digital Library
od 1916-01-01
Medline Complete (EBSCOhost)
od 1916-01-01 do Před 1 rokem
Health & Medicine (ProQuest)
od 2004-10-01 do 2020-12-31
Family Health Database (ProQuest)
od 2004-10-01 do 2020-12-31
Public Health Database (ProQuest)
od 2004-10-01 do 2020-12-31
- MeSH
- biologická evoluce MeSH
- chromozomy MeSH
- hybridní buňky cytologie fyziologie MeSH
- infertilita genetika MeSH
- meióza * MeSH
- partenogeneze * MeSH
- ryby genetika fyziologie MeSH
- vznik druhů (genetika) * MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Hybrid sterility is a hallmark of speciation, but the underlying molecular mechanisms remain poorly understood. Here, we report that speciation may regularly proceed through a stage at which gene flow is completely interrupted, but hybrid sterility occurs only in male hybrids whereas female hybrids reproduce asexually. We analyzed gametogenic pathways in hybrids between the fish species Cobitis elongatoides and C. taenia, and revealed that male hybrids were sterile owing to extensive asynapsis and crossover reduction among heterospecific chromosomal pairs in their gametes, which was subsequently followed by apoptosis. We found that polyploidization allowed pairing between homologous chromosomes and therefore partially rescued the bivalent formation and crossover rates in triploid hybrid males. However, it was not sufficient to overcome sterility. In contrast, both diploid and triploid hybrid females exhibited premeiotic genome endoreplication, thereby ensuring proper bivalent formation between identical chromosomal copies. This endoreplication ultimately restored female fertility but it simultaneously resulted in the obligate production of clonal gametes, preventing any interspecific gene flow. In conclusion, we demonstrate that the emergence of asexuality can remedy hybrid sterility in a sex-specific manner and contributes to the speciation process.
Department of Biology and Ecology Faculty of Science University of Ostrava 710 00 Czech Republic
Institute of Zoology Academy of Science of Moldova Chisinau MD 2028 Republic of Moldova
Museum of Natural History University of Wrocław 50 335 Poland
Citace poskytuje Crossref.org
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